Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1642152 | 0.87 | THRB (0.59) | THRATHRB | |
| SCHEMBL6663984 | 0.83 | THRA (0.66) | THRATHRB | |
| SCHEMBL6661540 | 0.82 | THRA (0.51) | THRATHRB | |
| SCHEMBL4964532 | 0.82 | THRB (0.53) | THRATHRB | |
| SCHEMBL4963674 | 0.81 | THRB (0.53) | THRATHRB | |
| SCHEMBL6657711 | 0.81 | THRA (0.53) | THRATHRB | |
| SCHEMBL4964533 | 0.80 | THRA (0.48) | THRATHRB | |
| SCHEMBL6689006 | 0.79 | THRA (0.55) | THRATHRB | |
| SCHEMBL6664358 | 0.78 | THRA (0.58) | THRATHRB | |
| SCHEMBL6659641 | 0.76 | THRA (0.58) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6664291-B2 | Aromatic amidealkyl acid or ester or amide or hydroxy derivatives are useful in the treatment of obesity, overweight condition, hyperlipidemia, glucoma, cardiac arrhythmias, thyroid disease, skin disoders and diabetes | PFIZER, INC. | 2003-12-16 | — | — | US | disclosed |