Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Decane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.89 |
| ▸ | THRB | P10828 | 1/20 | 0.89 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decane SCHEMBL8345709 | 1.00 | TSHR (0.89) | TSHRTHRBDNM1LMNAALDH1A1 | |
| Heptane SCHEMBL2316247 | 1.00 | — | — | |
| Dodecane SCHEMBL3296654 | 1.00 | TSHR (0.89) | TSHRTHRBDNM1LMNAALDH1A1 | |
| Octane SCHEMBL9775420 | 1.00 | TSHR (0.89) | TSHRTHRBDNM1LMNAALDH1A1 | |
| Nonane SCHEMBL9775414 | 1.00 | TSHR (0.89) | TSHRTHRBDNM1LMNAALDH1A1 | |
| Tetradecane SCHEMBL25287499 | 1.00 | TSHR (0.89) | TSHRTHRBDNM1LMNAALDH1A1 | |
| Nonane SCHEMBL9775419 | 1.00 | TSHR (0.89) | TSHRTHRBDNM1LMNAALDH1A1 | |
| Hexadecane SCHEMBL22470776 | 1.00 | TSHR (0.89) | TSHRTHRBDNM1LMNAALDH1A1 | |
| Decane SCHEMBL22470775 | 1.00 | TSHR (0.89) | TSHRTHRBDNM1LMNAALDH1A1 | |
| Decane SCHEMBL6294371 | 1.00 | TSHR (0.89) | TSHRTHRBDNM1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025002452-A1 | LIQUID ORGANIC COMPOSITION FOR LITHIUM EXTRACTION, AND PREPARATION METHOD THEREFOR | 北京索特莱克科技发展有限公司 | 2025-01-02 | — | — | WO | claimed |
| CN-119101050-A | Liquid crystal molecular compound and preparation method and application thereof | 长江师范学院 | 2024-12-10 | — | — | CN | claimed |
| CN-118185608-A | Janus carbon nano tube viscosity reducer particle, preparation method and thickened oil viscosity reducing method | 中海石油(中国)有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-116693785-B | Nitrogen-containing heterocyclic polymer, polymer film and application thereof | 武汉立膜科技有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-117285819-A | High-conductivity high-flexibility composite material, ion exchange membrane and application thereof | 武汉立膜科技有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-117285701-A | Nitrogen-containing heterocyclic polymer with cross-linking group at tail end, polymer film and application thereof | 武汉立膜科技有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-116693785-A | Nitrogen-containing heterocyclic polymer, polymer film and application thereof | 武汉立膜科技有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-116023333-A | Bio-based imidazole and preparation method and application thereof | 贵州大学 | 2023-04-28 | — | — | CN | claimed |
| CN-115417850-B | Application of catalyst containing spiro-cyclic compound in catalyzing reaction of epoxy compound and carbon dioxide | 深圳新宙邦科技股份有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-115745765-A | Preparation method of p-bromoalkylcyclohexanone compounds | 浙大宁波理工学院 | 2023-03-07 | — | — | CN | claimed |
| CN-115417850-A | Application of catalyst containing spiro-cyclic compound in catalyzing reaction of epoxy compound and carbon dioxide | 深圳新宙邦科技股份有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-114736657-A | Alkyl imidazole ionic liquid containing fatty acid group and preparation method and application thereof | 华南理工大学 | 2022-07-12 | — | — | CN | claimed |
| CN-111087392-B | Vinyl conjugated indolylaminothiazole compound and preparation method and application thereof | 西南大学 | 2022-06-03 | — | — | CN | claimed |
| CN-110669165-B | Cationic polyacrylate fluorine-free waterproof agent and preparation method thereof | 陕西科技大学 | 2022-04-12 | — | — | CN | claimed |
| CN-107540599-B | Aminoindane compounds and their use to treat pain | 阿萨纳生物科技有限责任公司 | 2021-06-04 | — | — | CN | claimed |
| WO-2014028675-A1 | USE OF AMINOINDANE COMPOUNDS IN TREATING OVERACTIVE BLADDER AND INTERSTITIAL CYSTITIS | ENDO PHARMACEUTICALS INC. (US) | 2014-02-20 | — | — | WO | claimed |
| US-12616964-B2 | Spirocyclic compound containing catalyst for use in catalyzing reaction of epoxide compound and carbon dioxide | SHENZHEN CAPCHEM TECHNOLOGY CO., LTD. (CN) | 2026-05-05 | — | — | US | disclosed |
| CN-119684319-A | A-DA' D-A type non-fullerene small molecule acceptor material based on inner linear alkyl, and preparation method and application thereof | 山东大学 | 2025-03-25 | — | — | CN | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |
| CN-87103235-A | The photosensitive azole pesticides | — | 1988-06-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12616964-B2 | Spirocyclic compound containing catalyst for use in catalyzing reaction of epoxide compound and carbon dioxide | RCC2, NR3C2, CA2 | TSHR 593/4885THRB 1644/4885DNM1 4284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.