Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7121033 | 0.86 | KDM4E (0.42) | GAAKDM4EALDH1A1MAPTUSP2 | |
| SCHEMBL7116591 | 0.86 | GAA (0.50) | GAAKDM4EALDH1A1MAPTUSP2 | |
| SCHEMBL11151986 | 0.81 | GAA (0.53) | GAAKDM4EALDH1A1MAPTUSP2 | |
| SCHEMBL15568434 | 0.80 | GAA (0.55) | GAAKDM4EALDH1A1MAPTUSP2 | |
| SCHEMBL7117957 | 0.80 | GAA (0.51) | GAAKDM4EALDH1A1MAPTUSP2 | |
| SCHEMBL462467 | 0.79 | KDM4E (0.49) | GAAKDM4EALDH1A1MAPTUSP2 | |
| SCHEMBL7121032 | 0.79 | GAA (0.46) | GAAKDM4EALDH1A1MAPTUSP2 | |
| SCHEMBL7120505 | 0.79 | GAA (0.50) | GAAKDM4EALDH1A1MAPTUSP2 | |
| SCHEMBL11150521 | 0.79 | GAA (0.55) | GAAKDM4EALDH1A1MAPTUSP2 | |
| Bromide SCHEMBL7124452 | 0.78 | GAA (0.50) | GAAKDM4EALDH1A1MAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359888-A1 | COUPLERS FOR OXIDATIVE COLORATION OF HAIR | P&G-Clairol, Inc. (US) | 2003-11-12 | — | — | EP | disclosed |
| US-20020144700-A1 | Couplers for oxidative coloration of hair | CLAIROL INCORPORATED | 2002-10-10 | — | — | US | disclosed |
| WO-2002058659-A1 | COUPLERS FOR OXIDATIVE COLORATION OF HAIR | P&G-CLAIROL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020144700-A1 | Couplers for oxidative coloration of hair | CBR1, CBR3, MT-CO1 | GAA 4787/4885KDM4E 2095/4885ALDH1A1 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.