Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714512 | 0.87 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL11814475 | 0.69 | — | — | |
| SCHEMBL15241474 | 0.68 | TSHR (0.33) | ALDH1A1 | |
| SCHEMBL16146939 | 0.66 | ALDH1A1 (0.36) | ALDH1A1 | |
| Acetic Acid SCHEMBL869816 | 0.64 | FFAR3 (0.35) | ALDH1A1 | |
| SCHEMBL14899030 | 0.64 | MME (0.37) | — | |
| SCHEMBL1172295 | 0.62 | MME (0.36) | ALDH1A1 | |
| SCHEMBL2160390 | 0.62 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL3257641 | 0.61 | TSHR (0.33) | ALDH1A1 | |
| SCHEMBL21457833 | 0.60 | TSHR (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124780-B2 | Benzimidazole compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-02-28 | — | — | US | disclosed |
| US-20070010542-A1 | Benzimidazole compound | EISAI CO., LTD. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010542-A1 | Benzimidazole compound | HRH2, GIPR, HRH4 | ALDH1A1 1028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.