Acetic Acid

Acetic Acid

SCHEMBL869816

CC(=O)O.CCC1(C)OCCO1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 3/20 0.35
LCK P06239 1/20 0.35
FYN P06241 1/20 0.35
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAPK1 P28482 1/20 0.32
PTPN1 P18031 1/20 0.31
ACP1 P24666 1/20 0.31
CDC25B P30305 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL15739028 0.87
SCHEMBL3671124 0.87
SCHEMBL969840 0.87
Ethylene Glycol SCHEMBL1876642 0.82
Methylene Chloride SCHEMBL4227657 0.79
SCHEMBL14321411 0.79 TTR (0.33)
SCHEMBL9587324 0.76
SCHEMBL3309034 0.76
SCHEMBL4097495 0.75 TSHR (0.39) ALDH1A1TSHRL3MBTL1MAPK1SMN1; SMN2
SCHEMBL9708919 0.75 MAPK1 (0.39) FFAR3MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100209374-A1 Multi-Phase Personal Care Composition Comprising a Stabilizing Perfume Composition WEI KARL SHIQING 2010-08-19 US claimed
US-7700528-B2 Multi-phase personal care composition comprising a stabilizing perfume composition THE PROCTER & GAMBLE COMPANY (US) 2010-04-20 US claimed
EP-1942861-A2 MULTI-PHASE PERSONAL CARE COMPOSITION COMPRISING A STABILIZING PERFUME COMPOSITION The Procter and Gamble Company (US) 2008-07-16 EP claimed
US-20070135319-A1 Multi-phase personal care composition comprising a stabilizing perfume composition PROCTER & GAMBLE COMPANY, THE 2007-06-14 US claimed
WO-2007052224-A2 MULTI-PHASE PERSONAL CARE COMPOSITION COMPRISING A STABILIZING PERFUME COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2007-05-10 WO claimed
US-20070071780-A1 Personal care composition comprising a perfume booster accord PROCTER & GAMBLE COMPANY, THE 2007-03-29 US claimed
WO-2024175295-A1 DETERGENTS AND CLEANING AGENTS COMPRISING DISPERSIN AND FRAGRANCE HENKEL AG & CO. KGAA (DE) 2024-08-29 WO disclosed
US-11896702-B2 Fragrance-enhancing compositions ALMENDRA PTE LTD. (SG) 2024-02-13 US disclosed
EP-4255384-A1 AQUEOUS HAIR CONDITIONER COMPOSITIONS CONTAINING SOLUBILIZED ANTI-DANDRUFF ACTIVES The Procter & Gamble Company (US) 2023-10-11 EP disclosed
US-20230303953-A1 CLEANING COMPOSITIONS AND USES THEREOF HENKEL AG & CO. KGAA (DE) 2023-09-28 US disclosed
CN-116568266-A Aqueous hair conditioner composition containing dissolved anti-dandruff active 宝洁公司 2023-08-08 CN disclosed
US-11672748-B2 Aqueous hair conditioner compositions containing solubilized anti-dandruff actives THE PROCTER & GAMBLE COMPANY (US) 2023-06-13 US disclosed
EP-4179054-A1 CLEANING COMPOSITIONS AND USES THEREOF Henkel AG & Co. KGaA (DE) 2023-05-17 EP disclosed
EP-1707185-A1 Solvent materials and methods for preparing fragrance compositions INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) 2006-10-04 EP disclosed
EP-1706532-A1 FABRIC ARTICLE TREATING DEVICE AND SYSTEM WITH SUGGESTIVE SCENT The Procter and Gamble Company (US) 2006-10-04 EP disclosed
EP-1633845-A2 VOLATILE MATERIAL DELIVERY METHOD The Procter & Gamble Company (US) 2006-03-15 EP disclosed
WO-2005073454-A1 FABRIC ARTICLE TREATING DEVICE AND SYSTEM WITH SUGGESTIVE SCENT THE PROCTER & GAMBLE COMPANY (US) 2005-08-11 WO disclosed
US-20050091879-A1 Volatile material delivery method THE PROCTER & GAMBLE COMPANY 2005-05-05 US disclosed
US-20050076533-A1 Fabric article treating device and system with suggestive scent PROCTER & GAMBLE COMPANY, THE 2005-04-14 US disclosed
WO-2004094580-A2 VOLATILE MATERIAL DELIVERY METHOD THE PROCTER & GAMBLE COMPANY (US) 2004-11-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135319-A1 Multi-phase personal care composition comprising a stabilizing perfume composition CUTA, PARG, POLG FFAR3 1865/4885LCK 4027/4885FYN 4499/4885
US-11672748-B2 Aqueous hair conditioner compositions containing solubilized anti-dandruff actives POLR1C, NACA, PIK3C3 FFAR3 692/4885LCK 1008/4885FYN 320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.