Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 16/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23944974 | 0.78 | OPRD1 (0.41) | OPRD1OPRM1OPRK1TSHR | |
| SCHEMBL4395137 | 0.77 | KDM4E (0.35) | — | |
| SCHEMBL11391893 | 0.77 | OPRD1 (0.40) | OPRD1OPRM1OPRK1TSHR | |
| SCHEMBL15132381 | 0.75 | OPRD1 (0.44) | OPRD1OPRM1OPRK1TSHR | |
| SCHEMBL4398046 | 0.74 | DRD2 (0.37) | OPRD1 | |
| SCHEMBL6692977 | 0.73 | OPRD1 (0.41) | OPRD1OPRK1 | |
| SCHEMBL327601 | 0.73 | OPRD1 (0.41) | OPRD1OPRK1 | |
| SCHEMBL290880 | 0.73 | — | — | |
| SCHEMBL3970107 | 0.73 | OPRD1 (0.41) | OPRD1OPRK1 | |
| SCHEMBL23735789 | 0.72 | OPRD1 (0.41) | OPRD1OPRM1OPRK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003047584-A1 | QUINOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2003-06-12 | — | — | WO | claimed |