Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14426986 | 0.85 | IDO1 (0.39) | IDO1CES2DAOACP1KIF11 | |
| SCHEMBL2376297 | 0.83 | IDO1 (0.44) | IDO1CES2DAOACP1KIF11 | |
| SCHEMBL496729 | 0.83 | ACP1 (0.50) | IDO1CES2DAOACP1KIF11 | |
| SCHEMBL773148 | 0.83 | IDO1 (0.44) | IDO1CES2DAOACP1KIF11 | |
| SCHEMBL4863519 | 0.83 | KIF11 (0.59) | IDO1CES2DAOACP1KIF11 | |
| SCHEMBL2376293 | 0.83 | IDO1 (0.44) | IDO1CES2DAOACP1KIF11 | |
| SCHEMBL27450225 | 0.79 | GAA (0.56) | IDO1DAOLMNAGAAKMT2A | |
| SCHEMBL3298424 | 0.78 | DAO (0.45) | IDO1CES2DAOACP1PPARG | |
| SCHEMBL341095 | 0.78 | PPARG (0.41) | IDO1CES2DAOACP1KIF11 | |
| SCHEMBL1776129 | 0.73 | IDO1 (0.52) | IDO1CES2DAORXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112251-B1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA SA (FR) | 2003-05-07 | — | — | EP | disclosed |
| EP-1112251-A1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000015609-A1 | AZETIDINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | AVENTIS PHARMA S.A. (FR) | 2000-03-23 | — | — | WO | disclosed |