SCHEMBL341095

SCHEMBL341095

CNS(=O)(=O)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.41
IDO1 P14902 2/20 0.40
MAPT P10636 1/20 0.40
DAO P14920 2/20 0.39
ACP1 P24666 1/20 0.39
GALR3 O60755 1/20 0.38
CYP2D6 P10635 1/20 0.38
KIF11 P52732 2/20 0.37
ACLY P53396 1/20 0.36
MTOR P42345 1/20 0.36
KDM4E B2RXH2 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TACR1 P25103 2/20 0.36
MLYCD O95822 1/20 0.36
CES2 O00748 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10154100 0.83 GALR3 (0.54) IDO1MAPTDAOGALR3
SCHEMBL9355 0.81 KIF11 (0.54) KIF11ACLY
SCHEMBL2376297 0.79 IDO1 (0.44) PPARGIDO1DAOACP1CYP2D6
SCHEMBL7127796 0.78 IDO1 (0.47) PPARGIDO1DAOACP1CYP2D6
SCHEMBL804895 0.75 GAA (0.43) MAPTKDM4EHTTTACR1
SCHEMBL4863519 0.75 KIF11 (0.59) PPARGIDO1DAOACP1CYP2D6
SCHEMBL773148 0.75 IDO1 (0.44) PPARGIDO1DAOACP1CYP2D6
SCHEMBL496729 0.75 ACP1 (0.50) PPARGIDO1DAOACP1CYP2D6
SCHEMBL2376293 0.75 IDO1 (0.44) PPARGIDO1DAOACP1CYP2D6
SCHEMBL12626816 0.73 POLB (0.34) PPARGIDO1MAPTACP1GALR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2582688-B1 ANTHRANILIC ACID DIAMIDE DERIVATIVES BAYER IP GMBH (DE) 2015-10-07 EP disclosed
US-8791139-B2 Anthranilic diamide derivatives BAYER CROPSCIENCE AG (DE) 2014-07-29 US disclosed
US-20120015980-A1 ANTHRANILIC DIAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120015980-A1 ANTHRANILIC DIAMIDE DERIVATIVES DDT, QDPR, ANTXR2 PPARG 2070/4885IDO1 479/4885MAPT 4576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.