SCHEMBL712805

SCHEMBL712805

NNC(=O)c1c(C(=O)O)ccc2c1ccc1ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.51
LDHA P00338 1/20 0.50
SOS1 Q07889 2/20 0.48
KDM4E B2RXH2 3/20 0.48
GAA P10253 3/20 0.48
MAPT P10636 3/20 0.48
ALDH1A1 P00352 2/20 0.48
NR4A1 P22736 1/20 0.46
NR4A2 P43354 1/20 0.46
NR4A3 Q92570 1/20 0.46
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
HIF1A Q16665 1/20 0.43
HPRT1 P00492 1/20 0.42
CSNK2A2 P19784 1/20 0.42
CSNK2B P67870 1/20 0.42
CSNK2A1 P68400 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5480836 0.92 WDR5 (0.56) WDR5LDHAKDM4EGAAMAPT
SCHEMBL712806 0.91 MAPT (0.50) WDR5LDHASOS1KDM4EGAA
SCHEMBL31613859 0.84 WDR5 (0.61) WDR5LDHASOS1KDM4EGAA
SCHEMBL11928243 0.84 WDR5 (0.61) WDR5LDHASOS1KDM4EGAA
SCHEMBL183135 0.84 WDR5 (0.61) WDR5LDHASOS1KDM4EGAA
SCHEMBL4944558 0.83 SOS1 (0.41) WDR5LDHASOS1KDM4EGAA
SCHEMBL856182 0.82 MAPT (0.50) WDR5LDHAKDM4EGAAMAPT
Hydrochloric Acid SCHEMBL3680894 0.82 LDHA (0.62) WDR5LDHASOS1KDM4EGAA
SCHEMBL5478033 0.81 GAA (0.50) KDM4EGAAMAPTALDH1A1CYP1A2
SCHEMBL4944563 0.81 SOS1 (0.40) WDR5LDHASOS1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108414736-B Method for detecting target object by using chemiluminescence enhancer modified antibody 江苏三联生物工程有限公司 2020-11-17 CN claimed
EP-2027453-B1 NONSEPARATION ASSAY METHODS BECKMAN COULTER INC (US) 2017-03-15 EP claimed
US-8124362-B2 Nonseparation assay methods BECKMAN COULTER, INC. (US) 2012-02-28 US claimed
US-20110318747-A1 Nonseparation Assay Methods BECKMAN COULTER, INC. (US) 2011-12-29 US claimed
US-8012705-B2 Nonseparation assay methods BECKMAN COULTER, INC. (US) 2011-09-06 US claimed
US-20110183361-A1 Nonseparation Assay Methods BECKMAN COULTER, INC. (US) 2011-07-28 US claimed
EP-2027453-A4 NONSEPARATION ASSAY METHODS BECKMAN COULTER INC (US) 2009-07-01 EP claimed
EP-2027453-A1 NONSEPARATION ASSAY METHODS Beckman Coulter, Inc. (US) 2009-02-25 EP claimed
WO-2007133988-A1 NONSEPARATION ASSAY METHODS BECKMAN COULTER, INC. (US) 2007-11-22 WO claimed
US-20070264664-A1 Nonseparation assay methods NEXGEN DIAGNOSTICS LLC 2007-11-15 US claimed
CN-112400113-B Specific binding chemiluminescence assay 3M创新有限公司 2022-04-15 CN disclosed
CN-112400025-A Measurement of 3M创新有限公司 2021-02-23 CN disclosed
CN-112400113-A Specific binding chemiluminescence assay 3M创新有限公司 2021-02-23 CN disclosed
CN-108414736-B Method for detecting target object by using chemiluminescence enhancer modified antibody 江苏三联生物工程有限公司 2020-11-17 CN disclosed