SCHEMBL7128052

SCHEMBL7128052

C=CCn1cnc2ccc(OC)cc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.54
MTNR1B P49286 1/20 0.54
ALDH1A1 P00352 2/20 0.50
HPGD P15428 2/20 0.50
HTT P42858 2/20 0.50
MAPK1 P28482 1/20 0.50
MAPK10 P53779 1/20 0.50
NCOA1 Q15788 1/20 0.50
NCOA3 Q9Y6Q9 1/20 0.50
PDE4B Q07343 2/20 0.45
PDE4D Q08499 1/20 0.45
BRD4 O60885 1/20 0.45
TBXA2R P21731 1/20 0.44
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
QPCT Q16769 2/20 0.42
MAPT P10636 3/20 0.41
KDM4E B2RXH2 2/20 0.41
CDYL2 Q8N8U2 1/20 0.41
CDYL Q9Y232 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7643046 0.88 FGFR1 (0.50) MTNR1AMTNR1BALDH1A1HPGDHTT
SCHEMBL10603795 0.81 MTNR1A (0.59) MTNR1AMTNR1BALDH1A1HPGDHTT
Bromide SCHEMBL29624933 0.80 MTNR1A (0.58) MTNR1AMTNR1BALDH1A1HPGDHTT
SCHEMBL19848085 0.80 TNF (0.44) ALDH1A1HPGDHTTMAPK1TBXA2R
SCHEMBL19911355 0.80 MTNR1A (0.58) MTNR1AMTNR1BALDH1A1HPGDHTT
SCHEMBL19911346 0.79 MTNR1A (0.64) MTNR1AMTNR1BALDH1A1HPGDHTT
SCHEMBL19611398 0.78 MTNR1A (0.62) MTNR1AMTNR1BALDH1A1HPGDHTT
SCHEMBL12479984 0.78 MTNR1A (0.62) MTNR1AMTNR1BALDH1A1HPGDHTT
SCHEMBL12479232 0.78 MTNR1A (0.66) MTNR1AMTNR1BALDH1A1HPGDHTT
SCHEMBL9120412 0.78 MTNR1A (0.62) MTNR1AMTNR1BALDH1A1HPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0271260-B1 Supersensitization of silver halide emulsions MINNESOTA MINING & MFG (US) 1995-01-04 EP claimed
US-4873184-A ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-10 US claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP claimed
US-10756394-B2 Nonaqueous electrolyte and nonaqueous secondary battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-08-25 US disclosed
EP-3467930-B1 NONAQUEOUS ELECTROLYTE AND NONAQUEOUS SECONDARY BATTERY ASAHI CHEMICAL IND (JP) 2020-05-13 EP disclosed
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-03-01 US disclosed
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-03-01 US disclosed
EP-3279997-A1 NONAQUEOUS ELECTROLYTE AND NONAQUEOUS SECONDARY BATTERY Asahi Kasei Kabushiki Kaisha (JP) 2018-02-07 EP disclosed
US-20030216582-A1 2-CARBOXAMIDE-BENZIMIDAZOLES USEFUL IN THE TREATMENT AND PREVENTION OF ISCHEMIC REPERFUSION INJURY NIKOLAIDES NICHOLAS (US) 2003-11-20 US disclosed
US-20030087943-A1 2-phencycarbamoyl-benzimidazoles NIKOLAIDES NICHOLAS (US) 2003-05-08 US disclosed
EP-1263736-A1 2-CARBOXAMIDE-BENZIMIDAZOLES USEFUL IN THE TREATMENT AND PREVENTION OF ISCHEMIC REPERFUSION INJURY THE PROCTER & GAMBLE COMPANY (US) 2002-12-11 EP disclosed
WO-2001058878-A1 2-CARBOXAMIDE-BENZIMIDAZOLES USEFUL IN THE TREATMENT AND PREVENTION OF ISCHEMIC REPERFUSION INJURY THE PROCTER & GAMBLE COMPANY (US) 2001-08-16 WO disclosed
EP-0271260-B1 Supersensitization of silver halide emulsions MINNESOTA MINING & MFG (US) 1995-01-04 EP disclosed
US-5013622-A Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-05-07 US disclosed
US-4873184-A ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-10 US disclosed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216582-A1 2-CARBOXAMIDE-BENZIMIDAZOLES USEFUL IN THE TREATMENT AND PREVENTION OF ISCHEMIC REPERFUSION INJURY CBR3, BAK1, CBR1 MTNR1A 349/4885MTNR1B 436/4885ALDH1A1 428/4885
US-20030087943-A1 2-phencycarbamoyl-benzimidazoles BRI3BP, CBR3, H1-3 MTNR1A 1692/4885MTNR1B 904/4885ALDH1A1 1676/4885
US-10756394-B2 Nonaqueous electrolyte and nonaqueous secondary battery BPTF, BRD4, KCNN2 MTNR1A 4313/4885MTNR1B 4134/4885ALDH1A1 3497/4885
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery BPTF, BRD4, KCNN2 MTNR1A 4313/4885MTNR1B 4134/4885ALDH1A1 3497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.