Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10575415 | 0.90 | KMT2A (0.67) | KMT2AHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL6687806 | 0.90 | LMNA (0.67) | KMT2AHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL3775206 | 0.90 | KMT2A (0.64) | KMT2AHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL29823822 | 0.90 | POLB (0.69) | KMT2AHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL5441319 | 0.90 | HSD17B10 (0.64) | KMT2AHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL8041564 | 0.90 | POLB (0.69) | KMT2AHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL15282130 | 0.90 | KMT2A (0.73) | KMT2AHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL9382762 | 0.90 | KMT2A (0.73) | KMT2AHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL10824134 | 0.89 | HSD17B10 (0.63) | KMT2AHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL28431713 | 0.88 | KMT2A (0.60) | KMT2AHSD17B10KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484451-A | Stable isotope labeled norfloxacin and synthetic method thereof | 上海安谱实验科技股份有限公司 | 2020-08-04 | — | — | CN | claimed |
| EP-3630779-B1 | ANTIBIOTIC RESISTANCE BREAKERS | KING S COLLEGE LONDON (GB) | 2025-09-03 | — | — | EP | disclosed |
| US-11746116-B2 | Antibiotic resistance breakers | KING'S COLLEGE LONDON (GB) | 2023-09-05 | — | — | US | disclosed |
| US-11746116-B2 | Antibiotic resistance breakers | KING'S COLLEGE LONDON (GB) | 2023-09-05 | — | — | US | disclosed |
| CN-110869373-B | Antibiotic resistance disruptors | 伦敦皇家学院 | 2023-03-07 | — | — | CN | disclosed |
| CN-108892639-B | Efficient and environment-friendly method for preparing quinolone compounds | 云南民族大学 | 2021-05-14 | — | — | CN | disclosed |
| CN-111484451-A | Stable isotope labeled norfloxacin and synthetic method thereof | 上海安谱实验科技股份有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-111484451-A | Stable isotope labeled norfloxacin and synthetic method thereof | 上海安谱实验科技股份有限公司 | 2020-08-04 | — | — | CN | disclosed |
| EP-3630779-A1 | ANTIBIOTIC RESISTANCE BREAKERS | Kings College London (GB) | 2020-04-08 | — | — | EP | disclosed |
| CN-110869373-A | Antibiotic resistance disruptors | 伦敦皇家学院 | 2020-03-06 | — | — | CN | disclosed |
| WO-2018220365-A1 | ANTIBIOTIC RESISTANCE BREAKERS | KING'S COLLEGE LONDON (GB) | 2018-12-06 | — | — | WO | disclosed |
| CN-108892639-A | A kind of method that high-efficiency environment friendly prepares carbostyril compound | 云南民族大学 | 2018-11-27 | — | — | CN | disclosed |
| EP-0793656-B1 | NOVEL BENZYL PYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2003-03-26 | — | — | EP | disclosed |
| US-6114351-A | N-oxides as antibacterial agents | BAYER AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |
| US-5763450-A | BACTERICIDES; TREATMENT OF INFECTIOUS DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| US-4956465-A | Bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746116-B2 | Antibiotic resistance breakers | ABCC1, ARL1, AKR1C3 | KMT2A 4080/4885HSD17B10 331/4885KDM4E 3599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.