Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 20/20 | 0.58 |
| ▸ | CTSS | P25774 | 14/20 | 0.58 |
| ▸ | CTSL | P07711 | 12/20 | 0.58 |
| ▸ | CTSB | P07858 | 7/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4714775 | 0.85 | CTSK (0.58) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6184379 | 0.82 | CTSL (0.59) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4711466 | 0.81 | CTSK (0.72) | CTSKCTSSCTSLCTSB | |
| SCHEMBL14291583 | 0.81 | CTSK (0.72) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4713449 | 0.80 | CTSK (0.64) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4716086 | 0.77 | CTSK (0.68) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4714342 | 0.77 | CTSK (0.68) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4714562 | 0.76 | CTSK (1.00) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4718811 | 0.75 | CTSK (0.56) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4714654 | 0.74 | CTSK (1.00) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6525036-B2 | Treating post-menopausal osteoporosis. | MERCK & CO., INC. | 2003-02-25 | — | — | US | disclosed |