SCHEMBL712810

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11633683	0.85	OPRM1 (0.51)	OPRM1OPRL1CTSLCTSBCTSK
	SCHEMBL29344720	0.84	TDP1 (0.39)	OPRM1OPRL1DPP4HRH3MAPT
	SCHEMBL31207743	0.84	OPRM1 (0.35)	OPRM1OPRL1CTSLCTSBCTSK
	SCHEMBL713481	0.83	OPRM1 (0.46)	OPRM1OPRL1CTSLCTSBCTSK
	SCHEMBL11559164	0.83	OPRM1 (0.46)	OPRM1OPRL1CTSLCTSBCTSK
	SCHEMBL31207762	0.82	CA1 (0.40)	OPRM1OPRL1TSHR
	SCHEMBL11633034	0.82	CTSL (0.45)	OPRM1OPRL1CTSLCTSBCTSK
	SCHEMBL28421079	0.80	CTSL (0.51)	OPRM1OPRL1CTSLCTSBCTSK
	SCHEMBL22594119	0.78	OPRM1 (0.53)	OPRM1OPRL1CTSLCTSBCTSK
	SCHEMBL1862005	0.78	TAAR1 (0.47)	CTSLCTSBCTSKSIGMAR1TMEM97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.