Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | SDHA | P31040 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CALML3 | P27482 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7126803 | 0.91 | MAOA (0.53) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7126944 | 0.90 | MAOA (0.49) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7118648 | 0.87 | MAOA (0.42) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7127131 | 0.87 | MAOA (0.42) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7117910 | 0.80 | MAOA (0.56) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7128538 | 0.78 | MAOA (0.46) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7119296 | 0.77 | MAOA (0.40) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL5838622 | 0.77 | MAOA (0.60) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL4957227 | 0.77 | MAOA (0.64) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL3326458 | 0.77 | MAOA (0.64) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216374-A1 | Antibiotic oxazolidinone derivatives | SYNGENTA LIMITED (GB) | 2003-11-20 | — | — | US | disclosed |
| US-6605630-B1 | Active against drug resistant gram positive pathogens | SYNGENTA LIMITED (GB) | 2003-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216374-A1 | Antibiotic oxazolidinone derivatives | OXA1L, HRH1, OGDH | MAOA 1078/4885MAOB 386/4885PTGS1 2772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.