Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14403436 | 0.91 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2SIGMAR1TDP1HSD17B10 | |
| SCHEMBL8913803 | 0.91 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2SIGMAR1TDP1HSD17B10 | |
| SCHEMBL26207612 | 0.91 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2SIGMAR1TDP1HSD17B10 | |
| SCHEMBL19088200 | 0.91 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2SIGMAR1TDP1HSD17B10 | |
| SCHEMBL16731669 | 0.90 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2SIGMAR1TDP1HSD17B10 | |
| SCHEMBL7131820 | 0.90 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2SIGMAR1TDP1HSD17B10 | |
| SCHEMBL8034106 | 0.90 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2SIGMAR1TDP1HSD17B10 | |
| SCHEMBL6860206 | 0.89 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2SIGMAR1TDP1HSD17B10 | |
| SCHEMBL22791264 | 0.88 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2SIGMAR1TDP1HSD17B10 | |
| SCHEMBL15834506 | 0.88 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2SIGMAR1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497926-B1 | MULTI-SITE METAL CHELATING AGENTS | NYCOMED SALUTAR INC (US) | 1998-06-03 | — | — | EP | claimed |
| US-5446145-A | Diagnostic imaging, detoxification, radiotherapy | NYCOMED SALUTAR, INC. (US) | 1995-08-29 | — | — | US | claimed |
| EP-0722442-B1 | POLYAZACYCLOALKANES AS DICHELANTS | NYCOMED SALUTAR INC (US) | 2003-01-15 | — | — | EP | disclosed |
| US-5972307-A | ADMINISTERING TO HUMAN OR ANIMAL BODY AN EFFECTIVE AMOUNT OF A DIAGNOSTIC AGENT COMPRISES A METAL CHELATE OF A COMPOUND HAVING TWO MACROCYCLIC CHELANT GROUPS LINKED BY A BRIDGE CONTAINING ESTER OR AMIDE BOND | NYCOMED SALUTAR, INC. (US) | 1999-10-26 | — | — | US | disclosed |
| EP-0497926-B1 | MULTI-SITE METAL CHELATING AGENTS | NYCOMED SALUTAR INC (US) | 1998-06-03 | — | — | EP | disclosed |
| US-5650133-A | CHELATING AGENTS USEFUL IN DIAGNOSTIC AND THERAPEUTIC COMPOSITIONS | NYCOMED SALUTAR (US) | 1997-07-22 | — | — | US | disclosed |
| US-5446145-A | Diagnostic imaging, detoxification, radiotherapy | NYCOMED SALUTAR, INC. (US) | 1995-08-29 | — | — | US | disclosed |
| WO-1995009848-A2 | POLYAZACYCLOALKANES AS DICHELANTS | NYCOMED SALUTAR, INC. (US) | 1995-04-13 | — | — | WO | disclosed |
| US-5281704-A | Polychelant compounds | SALUTAR, INC. (US) | 1994-01-25 | — | — | US | disclosed |
| EP-0497926-A1 | MULTI-SITE METAL CHELATING AGENTS | NYCOMED SALUTAR, INC. (US) | 1992-08-12 | — | — | EP | disclosed |
| WO-1991005762-A1 | MULTI-SITE METAL CHELATING AGENTS | COCKBAIN, JULIAN, RODERICK, MICHAELSON (GB) | 1991-05-02 | — | — | WO | disclosed |