Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128542 | 0.91 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2SIGMAR1TDP1TSHR | |
| SCHEMBL19088200 | 0.86 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2SIGMAR1TDP1TSHR | |
| SCHEMBL26207612 | 0.86 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2SIGMAR1TDP1TSHR | |
| SCHEMBL14403436 | 0.86 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2SIGMAR1TDP1TSHR | |
| SCHEMBL15834506 | 0.84 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2SIGMAR1TDP1MEN1 | |
| SCHEMBL9097900 | 0.84 | NPSR1 (0.48) | ALDH1A1NPSR1CYP2C19HSD17B10KDM4E | |
| SCHEMBL18118428 | 0.84 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2SIGMAR1TDP1MEN1 | |
| SCHEMBL7686018 | 0.83 | NPSR1 (0.44) | ALDH1A1SMN1; SMN2NPSR1TSHRHSD17B10 | |
| SCHEMBL16731669 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2SIGMAR1TDP1TSHR | |
| SCHEMBL7131820 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2SIGMAR1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170189568-A1 | UREA-BASED PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITORS FOR IMAGING AND THERAPY | FIVE ELEVEN PHARMA INC. | 2017-07-06 | — | — | US | disclosed |
| US-20170022224-A1 | HBED-Bisphosphonates, Radiometal Conjugates and Their Use as Theranostic Agents | FIVE ELEVEN PHARMA INC. (US) | 2017-01-26 | — | — | US | disclosed |
| WO-2017007790-A1 | HBED-BISPHOSPHONATES, RADIOMETAL CONJUGATES THEREOF AND THEIR USE AS THERANOSTIC AGENTS | FIVE ELEVEN PHARMA INC. (US) | 2017-01-12 | — | — | WO | disclosed |
| US-5679810-A | AMIDE OR ESTER LINKAGES; COMPLEXES PARAMAGNETIC METAL IONS; DIAGNOSTIC IMAGING | SALUTAR, INC. (US) | 1997-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189568-A1 | UREA-BASED PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) INHIBITORS FOR IMAGING AND THERAPY | KLK3, FOLH1, UTS2R | ALDH1A1 1860/4885SMN1; SMN2 4514/4885NPSR1 1589/4885 |
| US-20170022224-A1 | HBED-Bisphosphonates, Radiometal Conjugates and Their Use as Theranostic Agents | SLC10A1, SLC9B2, SLCO2B1 | ALDH1A1 1794/4885SMN1; SMN2 3463/4885NPSR1 439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.