Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TYMP | P19971 | 5/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19814711 | 1.00 | TK1 (0.47) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL8149970 | 1.00 | TK1 (0.47) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL1097570 | 1.00 | TK1 (0.47) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL856694 | 1.00 | TK1 (0.47) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL858969 | 1.00 | TK1 (0.47) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL14946298 | 1.00 | TK1 (0.47) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL14853815 | 1.00 | TK1 (0.47) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL19258430 | 1.00 | TK1 (0.47) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL2767589 | 1.00 | TK1 (0.47) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL5696111 | 1.00 | TK1 (0.47) | TK1ALDH1A1LMNAALBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670461-B1 | Bi-, tri, or polycyclic nucleoside analogues having a \"locked\" structure capable of forming heat resistant nucleobase specific duplexes and triplexes with single and double stranded nucleic acids. | EXIQON A/S (DK) | 2003-12-30 | — | — | US | disclosed |