SCHEMBL858969

SCHEMBL858969

Cc1cn([C@@H]2O[C@]3(CO)CO[C@H]2[C@H]3O)c(=O)[nH]c1=O

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TK1 P04183 4/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
ALB P02768 1/20 0.47
POLB P06746 1/20 0.47
ADRA1A P35348 1/20 0.47
BLM P54132 1/20 0.47
TYMP P19971 5/20 0.44
DHFR P00374 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19814711 1.00 TK1 (0.47) TK1ALDH1A1LMNAALBPOLB
SCHEMBL8149970 1.00 TK1 (0.47) TK1ALDH1A1LMNAALBPOLB
SCHEMBL1097570 1.00 TK1 (0.47) TK1ALDH1A1LMNAALBPOLB
SCHEMBL856694 1.00 TK1 (0.47) TK1ALDH1A1LMNAALBPOLB
SCHEMBL14946298 1.00 TK1 (0.47) TK1ALDH1A1LMNAALBPOLB
SCHEMBL14853815 1.00 TK1 (0.47) TK1ALDH1A1LMNAALBPOLB
SCHEMBL19258430 1.00 TK1 (0.47) TK1ALDH1A1LMNAALBPOLB
SCHEMBL2767589 1.00 TK1 (0.47) TK1ALDH1A1LMNAALBPOLB
SCHEMBL7128636 1.00 TK1 (0.47) TK1ALDH1A1LMNAALBPOLB
SCHEMBL5696111 1.00 TK1 (0.47) TK1ALDH1A1LMNAALBPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7034133-B2 Locked Nucleoside Analogues is a biochemical conjugate of nucleotides; as an aptamer in specific binding of antibiotics, drugs, amino acids, peptides, enzymes, saccharides, polysaccharides; heat resistance EXIQON A/S (DK) 2006-04-25 US claimed
EP-2099461-B1 LNA NUCLEOSIDE PHOSPHORAMIDATES SANTARIS PHARMA AS (DK) 2012-03-28 EP disclosed
EP-1178999-B1 L-RIBO-LNA ANALOGUES SANTARIS PHARMA AS (DK) 2007-03-14 EP disclosed
US-7053207-B2 L-ribo-LNA analogues EXIQON A/S (DK) 2006-05-30 US disclosed
US-20030087230-A1 L-Ribo-LNA analogues SANTARIS PHARMA A/S (DK) 2003-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030087230-A1 L-Ribo-LNA analogues RNGTT, NCL, RNASEL TK1 191/4885ALDH1A1 2132/4885LMNA 405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.