SCHEMBL7129049

SCHEMBL7129049

CC(OC(C)(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.55
ALDH1A1 P00352 3/20 0.50
ALOX15 P16050 1/20 0.50
TAAR1 Q96RJ0 1/20 0.44
ESR1 P03372 2/20 0.42
ESR2 Q92731 2/20 0.42
CYP3A4 P08684 1/20 0.42
KCNN4 O15554 4/20 0.42
TSHR P16473 2/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
CYP2B6 P20813 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9576890 0.82 MAPK1 (0.62) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL664301 0.80 MAPK1 (0.52) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL3887648 0.79 MAPK1 (0.46) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL6151736 0.78 MAPK1 (0.50) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL5545787 0.78 ALDH1A1 (0.65) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL7800340 0.78 MAPK1 (0.50) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL3676402 0.78 MAPK1 (0.50) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL8426498 0.78 MAPK1 (0.50) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL9114155 0.78 MAPK1 (0.50) MAPK1ALDH1A1ALOX15TAAR1ESR1
SCHEMBL675685 0.78 MAPK1 (0.50) MAPK1ALDH1A1ALOX15TAAR1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1966244-A PVDC composite film for seven-layer coextrusion processing and its method ZHANG XIAOMING (CN) 2007-05-23 CN claimed
CN-1291953-C Process for the preparation of styrene or substituted styrene SHELL INT RESEARCH (NL) 2006-12-27 CN claimed
CN-115480449-A Curable composition, cured product, and method for producing cured product 东京应化工业株式会社 2022-12-16 CN disclosed
CN-1966244-A PVDC composite film for seven-layer coextrusion processing and its method ZHANG XIAOMING (CN) 2007-05-23 CN disclosed
CN-1304648-C Bismuth sodium potassium titanate series nonlead ferroelectric piezoelectric monocrystal and its growing method and equipment UNIV SHANDONG (CN) 2007-03-14 CN disclosed
CN-1693542-A Bismuth sodium potassium titanate series nonlead ferroelectric piezoelectric monocrystal and its growing method and equipment UNIV SHANDONG (CN) 2005-11-09 CN disclosed
EP-1000005-B1 PROCESS FOR THE PREPARATION OF 1-(3,4-DIMETHOXYPHENYL)ETHANOL AGRO CHEMIE NOEVENYVEDOESZER G (HU) 2003-05-21 EP disclosed
US-6403843-B1 REDUCTION OF 3,4-DIMETHOXYACETOPHENONE WITH HYDROGEN UNDER AQUEOUS CONDITIONS USING A RANEY NICKEL CATALYST; HIGH YIELD; PRODUCT CRYSTALS CAN BE EASILY FILTERED AGRO-CHEMIE (HU) 2002-06-11 US disclosed
EP-0976708-B1 Cycloalkyl ethers and perfume compositions containing them PFW AROMA CHEM (NL) 2002-03-20 EP disclosed
US-6319889-B1 FRAGRANCES PFW AROMA CHEMICALS B.V. (NL) 2001-11-20 US disclosed
EP-1115487-A1 SUPPORTED BF3-COMPLEX SOLID ACID CATALYST, PREPARATION AND USE THE UNIVERSITY OF YORK (GB) 2001-07-18 EP disclosed
WO-2000013792-A1 SUPPORTED BF3-COMPLEX SOLID ACID CATALYST, PREPARATION AND USE THE UNIVERSITY OF YORK (GB) 2000-03-16 WO disclosed
EP-0976708-A1 Cycloalkyl ethers and perfume compositions containing them PFW AROMA CHEMICALS B.V. (NL) 2000-02-02 EP disclosed
CN-1240208-A Process for preparing 3-arylsulfur hydroxamic acids HOFFMANN LA ROCHE (CH) 2000-01-05 CN disclosed
US-4350825-A SEVERAL CATALYTIC PROCESSES STARTING WITH TOLUENE EXXON RESEARCH & ENGINEERING CO. (US) 1982-09-21 US disclosed
EP-0004732-B1 PREPARATION OF 2-PHENYLETHANOL AND 2-PHENYLETHYL ACETATE CHEM SYSTEMS, Inc. (US) 1981-12-23 EP disclosed