Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940811 | 1.00 | HTT (0.34) | HTTHSD17B10DNM1TDP1 | |
| SCHEMBL9656058 | 0.85 | — | — | |
| SCHEMBL237587 | 0.83 | CYP3A4 (0.32) | HSD17B10TDP1 | |
| SCHEMBL1173444 | 0.80 | ALDH1A1 (0.33) | — | |
| SCHEMBL11138371 | 0.79 | DNM1 (0.34) | HTTDNM1 | |
| SCHEMBL12818983 | 0.77 | CYP3A4 (0.46) | HTTHSD17B10TDP1 | |
| SCHEMBL17262665 | 0.77 | CYP3A4 (0.46) | HTTHSD17B10TDP1 | |
| SCHEMBL22135574 | 0.76 | HSD17B10 (0.41) | HSD17B10TDP1 | |
| Water SCHEMBL11575111 | 0.74 | HSD17B10 (0.34) | HSD17B10TDP1 | |
| SCHEMBL15329553 | 0.73 | HSD17B10 (0.43) | HTTHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307236-A2 | USE OF METAL COMPLEXES CONTAINING PERFLUOROALKYL AS CONTRAST AGENTS IN MR-IMAGING FOR THE REPRESENTATION OF PLAQUES, TUMOURS AND NECROSES | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002013874-A2 | USE OF METAL COMPLEXES CONTAINING PERFLUOROALKYL AS CONTRAST AGENTS IN MR-IMAGING FOR THE REPRESENTATION OF PLAQUES, TUMOURS AND NECROSES | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-02-21 | — | — | WO | disclosed |