Acrylamide

Acrylamide

SCHEMBL7129210

C=CC(N)=O.CC/C=C(\C(=O)O)N(C)C

nearest known ligand 0.41

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TSHR P16473 2/20 0.41
FGFR4 P22455 1/20 0.41
GRIK1 P39086 1/20 0.33
GRIK2 Q13002 1/20 0.33
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylamide SCHEMBL2928678 0.96 ALDH1A1 (0.38) ALDH1A1TSHRFGFR4GRIK1GRIK2
Acrylic Acid SCHEMBL4974396 0.90 LMNA (0.42) ALDH1A1TSHRGRIK1GRIK2LMNA
SCHEMBL119131 0.86 GRIK1 (0.36) ALDH1A1GRIK1GRIK2
SCHEMBL1531389 0.86 GRIK1 (0.36) ALDH1A1GRIK1GRIK2
Hydrochloric Acid SCHEMBL1155809 0.84 GRIK1 (0.35) ALDH1A1GRIK1GRIK2
Acetic Acid SCHEMBL11512956 0.82 GRIK1 (0.34) GRIK1GRIK2
Chloromethane SCHEMBL124967 0.82 GRIK1 (0.34) ALDH1A1TSHRGRIK1GRIK2
Bromomethane SCHEMBL7095814 0.82 GRIK1 (0.34) GRIK1GRIK2
Chloromethane SCHEMBL17049368 0.81 TDP1 (0.40) GRIK1GRIK2
Acrylamide SCHEMBL7132401 0.81 ALDH1A1 (0.37) ALDH1A1TSHRFGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0116151-B1 PROCESS FOR THE REGENERATION OR RECYCLING OF AQUEOUS DEGREASING AND CLEANING SOLUTIONS Henkel Kommanditgesellschaft auf Aktien (DE) 1987-05-20 EP claimed
US-6667374-B2 Prepared by a process in which a small quantity of a chain branching agent is added to the polymerization reaction mixture continuously or stepwise while the monomers are polymerized. ECOLE POLYTECHNIQUE FEDERAL DE LAUSANNE (CH) 2003-12-23 US disclosed
US-6617402-B2 Addition polymerization ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2003-09-09 US disclosed
US-6294622-B1 PROVIDING POLYMERIZATION REACTION MIXTURE COMPRISING POLYMERIZABLE ACRYLIC MONOMERS; POLYMERIZING ACRYLIC MONOMERS WHILE ADDING TO REACTION MIXTURE A CHAIN BRANCHING AGENT CONTINUOUSLY OR SEMI-CONTINUOUSLY ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2001-09-25 US disclosed
WO-1995027826-A1 PRE-PASTED WALLCOVERINGS AND THEIR PRODUCTION ALLIED COLLOIDS LIMITED (GB) 1995-10-19 WO disclosed