SCHEMBL7129241

SCHEMBL7129241

CC(=O)NC[C@H]1CN(c2ccc(C3=CCN(C=O)C(CO)C3)cc2)C(=O)O1

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.49
MAOB P27338 2/20 0.49
PTGS1 P23219 2/20 0.49
SDHA P31040 2/20 0.49
LMNA P02545 1/20 0.49
CALML3 P27482 1/20 0.49
F10 P00742 5/20 0.44
ABCB11 O95342 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7117877 0.87 MAOA (0.47) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7118695 0.86 MAOA (0.47) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7131117 0.84 MAOA (0.45) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7126766 0.83 MAOA (0.45) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6398619 0.82 MAOA (0.51) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6398610 0.82 MAOA (0.51) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7131122 0.82 MAOA (0.47) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7023494 0.81 MAOA (0.51) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7124678 0.80 MAOA (0.47) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7126743 0.79 MAOA (0.52) MAOAMAOBPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030216374-A1 Antibiotic oxazolidinone derivatives SYNGENTA LIMITED (GB) 2003-11-20 US disclosed
EP-1005468-A1 ANTIBIOTIC OXAZOLIDINONE DERIVATIVES ZENECA LIMITED (GB) 2000-06-07 EP disclosed
WO-1999010342-A1 ANTIBIOTIC OXAZOLIDINONE DERIVATIVES ZENECA LIMITED (GB) 1999-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216374-A1 Antibiotic oxazolidinone derivatives OXA1L, HRH1, OGDH MAOA 1078/4885MAOB 386/4885PTGS1 2772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.