Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129251 | 1.00 | ADORA1 (0.55) | ADORA1ADORA2AADORA2BADORA3TSHR | |
| SCHEMBL6572787 | 0.92 | ADORA1 (0.55) | ADORA1ADORA2AADORA2BADORA3TSHR | |
| SCHEMBL6572785 | 0.92 | ADORA1 (0.55) | ADORA1ADORA2AADORA2BADORA3TSHR | |
| SCHEMBL6573093 | 0.88 | ADORA1 (0.48) | ADORA1ADORA2AADORA2BADORA3TSHR | |
| SCHEMBL6575528 | 0.88 | ADORA3 (0.63) | ADORA1ADORA2AADORA2BADORA3TSHR | |
| SCHEMBL6574692 | 0.87 | ADORA1 (0.56) | ADORA1ADORA2AADORA2BADORA3TSHR | |
| SCHEMBL6576768 | 0.87 | ADORA1 (0.56) | ADORA1ADORA2AADORA2BADORA3TSHR | |
| SCHEMBL6574690 | 0.83 | ADORA1 (0.49) | ADORA1ADORA2AADORA2BADORA3TSHR | |
| SCHEMBL6572642 | 0.83 | ADORA1 (0.55) | ADORA1ADORA2AADORA2BADORA3TSHR | |
| SCHEMBL6572645 | 0.83 | ADORA1 (0.55) | ADORA1ADORA2AADORA2BADORA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3378240-B2 | — | — | 2003-02-17 | — | — | JP | claimed |
| JP-2002518509-A | — | — | 2002-06-25 | — | — | JP | claimed |
| EP-1090019-A1 | ADENOSINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2001-04-11 | — | — | EP | claimed |
| WO-1999067262-A1 | ADENOSINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-12-29 | — | — | WO | claimed |
| EP-1090019-A1 | ADENOSINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067262-A1 | ADENOSINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-12-29 | — | — | WO | disclosed |