Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574690 | 0.95 | ADORA1 (0.49) | ADORA1ADORA2AADORA2BADORA3TSHR | |
| SCHEMBL6576874 | 0.90 | ADORA3 (0.51) | ADORA1ADORA2AADORA2BADORA3RXFP1 | |
| SCHEMBL6574494 | 0.88 | ADORA3 (0.41) | ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL7129259 | 0.88 | ADORA1 (0.55) | ADORA1ADORA2AADORA2BADORA3TSHR | |
| SCHEMBL7129251 | 0.88 | ADORA1 (0.55) | ADORA1ADORA2AADORA2BADORA3TSHR | |
| SCHEMBL6574625 | 0.86 | ADORA1 (0.48) | ADORA1ADORA2AADORA2BADORA3TSHR | |
| SCHEMBL6576751 | 0.85 | ADORA3 (0.51) | ADORA1ADORA2AADORA2BADORA3RXFP1 | |
| SCHEMBL6572785 | 0.84 | ADORA1 (0.55) | ADORA1ADORA2AADORA2BADORA3TSHR | |
| SCHEMBL6572787 | 0.84 | ADORA1 (0.55) | ADORA1ADORA2AADORA2BADORA3TSHR | |
| SCHEMBL6575528 | 0.82 | ADORA3 (0.63) | ADORA1ADORA2AADORA2BADORA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090019-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-09-29 | — | — | EP | claimed |