SCHEMBL7129262

SCHEMBL7129262

CCN(CCN(CCN(CC)CC(=O)OC(C)(C)C)CC(=O)O)CC(=O)OC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.47
BLM P54132 2/20 0.47
PMP22 Q01453 2/20 0.47
CHRM2 P08172 2/20 0.47
KDM4E B2RXH2 1/20 0.47
LMNA P02545 1/20 0.47
ADRA2A P08913 1/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
DRD1 P21728 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
CYP2C19 P33261 1/20 0.47
ADRA1A P35348 1/20 0.47
DRD3 P35462 1/20 0.47
SLC6A3 Q01959 1/20 0.47
HRH3 Q9Y5N1 1/20 0.47
EYA2 O00167 1/20 0.43
APP P05067 1/20 0.43
ACE P12821 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29679201 0.92 TDP1 (0.40) TDP1BLMPMP22CHRM2KDM4E
SCHEMBL7567960 0.91 CHRM2 (0.37) TDP1BLMPMP22CHRM2KDM4E
SCHEMBL4621864 0.91 TDP1 (0.58) TDP1BLMPMP22CHRM2KDM4E
SCHEMBL992084 0.91 TDP1 (0.58) TDP1BLMPMP22CHRM2KDM4E
SCHEMBL2137303 0.91 TDP1 (0.38) TDP1BLMPMP22CHRM2KDM4E
SCHEMBL438113 0.91 TDP1 (0.58) TDP1BLMPMP22CHRM2KDM4E
SCHEMBL23711054 0.91 CA12 (0.36) TDP1BLMPMP22CHRM2KDM4E
SCHEMBL8130601 0.87 TDP1 (0.36) TDP1BLMPMP22CHRM2KDM4E
SCHEMBL14448133 0.87 TDP1 (0.38) TDP1BLMPMP22CHRM2KDM4E
SCHEMBL6859731 0.86 TDP1 (0.47) TDP1BLMPMP22CHRM2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1307236-A2 USE OF METAL COMPLEXES CONTAINING PERFLUOROALKYL AS CONTRAST AGENTS IN MR-IMAGING FOR THE REPRESENTATION OF PLAQUES, TUMOURS AND NECROSES SCHERING AKTIENGESELLSCHAFT (DE) 2003-05-07 EP disclosed
WO-2002013874-A2 USE OF METAL COMPLEXES CONTAINING PERFLUOROALKYL AS CONTRAST AGENTS IN MR-IMAGING FOR THE REPRESENTATION OF PLAQUES, TUMOURS AND NECROSES SCHERING AKTIENGESELLSCHAFT (DE) 2002-02-21 WO disclosed