Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | EYA2 | O00167 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621864 | 1.00 | TDP1 (0.58) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL992084 | 1.00 | TDP1 (0.58) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL19458 | 0.92 | TDP1 (0.42) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL437106 | 0.92 | TDP1 (0.48) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL6859731 | 0.91 | TDP1 (0.47) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL7129262 | 0.91 | TDP1 (0.47) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL419703 | 0.90 | TDP1 (0.42) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL18145576 | 0.90 | TDP1 (0.42) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL6227790 | 0.89 | TDP1 (0.45) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL19952793 | 0.89 | TDP1 (0.45) | TDP1BLMPMP22KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117327148-B | Preparation and application of polypeptide targeting brain glioma and radionuclide labeled molecular probe | 中国科学院近代物理研究所 | 2024-11-15 | — | — | CN | claimed |
| CN-117362392-A | ANGPT 2-targeted polypeptide and radioactive molecular probe for diagnosing brain glioma | 中国科学院近代物理研究所 | 2024-01-09 | — | — | CN | claimed |
| US-12527886-B2 | Radiopharmaceuticals and composition for thrombus imaging | THE ASAN FOUNDATION (KR) | 2026-01-20 | — | — | US | disclosed |
| CN-119431501-A | Diagnosis and treatment probe targeting HER2 receptor, and labeling precursor, preparation method and application thereof | 复旦大学附属中山医院 | 2025-02-14 | — | — | CN | disclosed |
| CN-118955620-A | Compounds comprising fibroblast activation protein ligands and uses thereof | 3B制药有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-117327148-B | Preparation and application of polypeptide targeting brain glioma and radionuclide labeled molecular probe | 中国科学院近代物理研究所 | 2024-11-15 | — | — | CN | disclosed |
| CN-118930608-A | Compounds comprising fibroblast activation protein ligands and uses thereof | 3B制药有限公司 | 2024-11-12 | — | — | CN | disclosed |
| US-20240368223-A1 | SITE-SPECIFIC RADIOISOTOPE-LABELED ANTIBODY USING IgG-BINDING PEPTIDE | KAGOSHIMA UNIVERSITY (JP) | 2024-11-07 | — | — | US | disclosed |
| WO-2024220548-A2 | MOLECULAR-MRI USING CCR2-TARGETED MICELLES FOR DETECTION OF LYMPH NODE METASTASES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2024-10-24 | — | — | WO | disclosed |
| CN-114341158-B | Compounds comprising fibroblast activation protein ligands and uses thereof | 3B制药有限公司 | 2024-08-06 | — | — | CN | disclosed |
| EP-3470418-B1 | SITE-SPECIFIC RADIOISOTOPE-LABELED ANTIBODY USING IGG-BINDING PEPTIDE | UNIV KAGOSHIMA (JP) | 2024-07-31 | — | — | EP | disclosed |
| EP-1720575-B1 | THERAPEUTIC AND DIAGNOSTIC CONJUGATES FOR USE WITH MULTISPECIFIC ANTIBODIES | IMMUNOMEDICS INC (US) | 2015-05-20 | — | — | EP | disclosed |
| US-8158573-B2 | Therapeutic and diagnostic conjugates for use with multispecific antibodies | IMMUNOMEDICS, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-8158573-B2 | Therapeutic and diagnostic conjugates for use with multispecific antibodies | IMMUNOMEDICS, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-20120063993-A1 | THERAPEUTIC AND DIAGNOSTIC CONJUGATES FOR USE WITH MULTISPECIFIC ANTIBODIES | IMMUNOMEDICS, INC. (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120063993-A1 | THERAPEUTIC AND DIAGNOSTIC CONJUGATES FOR USE WITH MULTISPECIFIC ANTIBODIES | IMMUNOMEDICS, INC. (US) | 2012-03-15 | — | — | US | disclosed |
| US-7405320-B2 | Therapeutic and diagnostic conjugates for use with multispecific antibodies | IMMUNOMEDICS, INC. (US) | 2008-07-29 | — | — | US | disclosed |
| US-7405320-B2 | Therapeutic and diagnostic conjugates for use with multispecific antibodies | IMMUNOMEDICS, INC. (US) | 2008-07-29 | — | — | US | disclosed |
| US-7405320-B2 | Therapeutic and diagnostic conjugates for use with multispecific antibodies | IMMUNOMEDICS, INC. (US) | 2008-07-29 | — | — | US | disclosed |
| US-20050002945-A1 | Therapeutic and diagnostic conjugates for use with multispecific antibodies | IMMUNOMEDICS, INC. | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050002945-A1 | Therapeutic and diagnostic conjugates for use with multispecific antibodies | TST, GLUL, TGM3 | TDP1 4777/4885BLM 3007/4885PMP22 1059/4885 |
| US-20240368223-A1 | SITE-SPECIFIC RADIOISOTOPE-LABELED ANTIBODY USING IgG-BINDING PEPTIDE | FCGR3B, NGLY1, FCGR2A | TDP1 3658/4885BLM 3210/4885PMP22 4325/4885 |
| US-12527886-B2 | Radiopharmaceuticals and composition for thrombus imaging | F11, CD274, SERPINC1 | TDP1 3450/4885BLM 3622/4885PMP22 2170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.