Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17260882 | 0.69 | EPHX1 (0.36) | MEN1CYP2C19KMT2ASIRT1EPHX1 | |
| SCHEMBL7938848 | 0.63 | KMT2A (0.40) | MEN1CYP2C19KMT2ASIRT1EPHX1 | |
| SCHEMBL21617570 | 0.62 | MEN1 (0.55) | MEN1CYP2C19KMT2ASIRT1 | |
| SCHEMBL13090620 | 0.62 | TSHR (0.43) | CYP2C19 | |
| SCHEMBL3893413 | 0.62 | TSHR (0.43) | CYP2C19 | |
| SCHEMBL96576 | 0.62 | TSHR (0.43) | CYP2C19 | |
| SCHEMBL7071503 | 0.61 | EPHX1 (0.31) | EPHX1 | |
| SCHEMBL5776726 | 0.61 | TSHR (0.38) | MEN1CYP2C19KMT2ASIRT1 | |
| Ammonia Solution, Strong SCHEMBL5430573 | 0.60 | TSHR (0.42) | CYP2C19 | |
| SCHEMBL3579154 | 0.60 | MEN1 (0.34) | MEN1CYP2C19KMT2ASIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1138769-C | Process for synthesis of 5-(-hydroxyalkyl) benzo [1,3] dioxols | �����ɷ� | 2004-02-18 | — | — | CN | disclosed |
| EP-1140894-B1 | PROCESS FOR THE SYNTHESIS OF 5-(ALPHA -HYDROXYALKYL) BENZO 1, 3]DIOXOLS | ENDURA SPA (IT) | 2003-12-17 | — | — | EP | disclosed |
| US-6342613-B1 | REACTING PYROCATECHOL WITH DIHALO- OR DI-ALKOXYALKANE, ACYLATING BENZO(1,3)DIOXOLE DERIVATIVE FORMED IN PRESENCE OF CATALYST, REDUCING TO 5-(ALPHA-HYDROXYALKYL)BENZO(1,3)DIOXOLE | ENDURA S.P.A. (IT) | 2002-01-29 | — | — | US | disclosed |
| US-6342613-B1 | REACTING PYROCATECHOL WITH DIHALO- OR DI-ALKOXYALKANE, ACYLATING BENZO(1,3)DIOXOLE DERIVATIVE FORMED IN PRESENCE OF CATALYST, REDUCING TO 5-(ALPHA-HYDROXYALKYL)BENZO(1,3)DIOXOLE | ENDURA S.P.A. (IT) | 2002-01-29 | — | — | US | disclosed |
| CN-1332736-A | Process for synthesis of 5-(-hydroxyalkyl) benzo [1,3] dioxols | ENDURA SPA (IT) | 2002-01-23 | — | — | CN | disclosed |
| EP-1140894-A1 | PROCESS FOR THE SYNTHESIS OF 5-(ALPHA -HYDROXYALKYL) BENZO 1, 3]DIOXOLS | ENDURA S.p.A. (IT) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040575-A1 | PROCESS FOR THE SYNTHESIS OF 5-(α -HYDROXYALKYL) BENZO[1, 3]DIOXOLS | ENDURA S.P.A. (IT) | 2000-07-13 | — | — | WO | disclosed |