Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594614 | 0.78 | ALDH1A1 (0.33) | MEN1KMT2ACYP2C19SIRT1LMNA | |
| SCHEMBL21617570 | 0.68 | MEN1 (0.55) | MEN1KMT2ACYP2C19SIRT1LMNA | |
| SCHEMBL7938848 | 0.65 | KMT2A (0.40) | MEN1KMT2ACYP2C19SIRT1LMNA | |
| SCHEMBL14673917 | 0.64 | HSD17B10 (0.39) | MEN1KMT2ACYP2C19LMNAPOLB | |
| SCHEMBL5373713 | 0.63 | ALDH1A1 (0.38) | MEN1KMT2ALMNAPOLB | |
| SCHEMBL5776726 | 0.63 | TSHR (0.38) | MEN1KMT2ACYP2C19SIRT1LMNA | |
| SCHEMBL490963 | 0.62 | CYP2C19 (0.46) | MEN1KMT2ACYP2C19SIRT1LMNA | |
| SCHEMBL7168733 | 0.62 | CYP2C19 (0.46) | MEN1KMT2ACYP2C19SIRT1LMNA | |
| SCHEMBL2587453 | 0.61 | MGLL (0.46) | MEN1KMT2ASIRT1LMNAPOLB | |
| SCHEMBL65759 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741323-B2 | Indene derivatives and process for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-22 | — | — | US | disclosed |
| US-20070185109-A1 | Idene derivatives and process for the preparation thereof | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2007-08-09 | — | — | US | disclosed |
| EP-1740531-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005100303-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185109-A1 | Idene derivatives and process for the preparation thereof | INSR, PPARD, GPR119 | MEN1 2055/4885KMT2A 3388/4885CYP2C19 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.