Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3767655 | 0.84 | ALDH1A1 (0.39) | KMT2AMEN1LMNAALDH1A1KDM4E | |
| SCHEMBL5373713 | 0.81 | ALDH1A1 (0.38) | KMT2AMEN1POLBLMNAALDH1A1 | |
| SCHEMBL232142 | 0.80 | UNG (0.45) | KMT2AMEN1POLBSIRT1ALDH1A1 | |
| SCHEMBL5391673 | 0.79 | CA12 (0.37) | KMT2AMEN1POLBALDH1A1KDM4E | |
| SCHEMBL1671260 | 0.79 | NOTUM (0.33) | HDAC4 | |
| SCHEMBL1446431 | 0.74 | MAPT (0.39) | KMT2APOLBLMNAALDH1A1KDM4E | |
| SCHEMBL230546 | 0.69 | CTRB1 (0.36) | — | |
| SCHEMBL21617570 | 0.68 | MEN1 (0.55) | KMT2AMEN1POLBLMNASIRT1 | |
| SCHEMBL422233 | 0.67 | PARP1 (0.44) | SIRT1ALDH1A1KDM4ETSHRSIRT2 | |
| SCHEMBL27635617 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262090-B1 | Aminopyridine-containing thiourea inhibitors of herpes viruses | AMERICAN HOME PRODUCTS CORPORATION | 2001-07-17 | — | — | US | disclosed |