SCHEMBL7129391

SCHEMBL7129391

NCCCC[C@@H](C(=O)O)N(Cc1ccccc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPOR P19235 4/20 0.49
CPB2 Q96IY4 2/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
MMP2 P08253 2/20 0.43
F2 P00734 1/20 0.42
MC4R P32245 1/20 0.41
MC5R P33032 1/20 0.41
MC3R P41968 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
HSD17B10 Q99714 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAOA P21397 1/20 0.41
MMP9 P14780 1/20 0.40
GSR P00390 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19100377 1.00 EPOR (0.49) EPORCPB2MEN1KMT2AMMP2
SCHEMBL21461808 0.95 EPOR (0.44) EPORCPB2MEN1KMT2AMC4R
SCHEMBL8465298 0.91 EPOR (0.47) EPORCPB2MEN1KMT2AMMP2
SCHEMBL1388218 0.89 EPOR (0.46) EPORCPB2MEN1KMT2AMMP2
SCHEMBL27462544 0.89 EPOR (0.46) EPORCPB2MEN1KMT2AMMP2
SCHEMBL2723861 0.86 EPOR (0.59) EPORCPB2MMP2F2MC4R
SCHEMBL2723866 0.86 EPOR (0.59) EPORCPB2MMP2F2MC4R
SCHEMBL7379793 0.86 CPB2 (0.48) EPORCPB2F2MC4RMC5R
Lysine SCHEMBL18114001 0.85 MMP2 (0.51) CPB2KMT2AMMP2MC4RMC5R
SCHEMBL30417019 0.85 EPOR (0.54) EPORCPB2ALDH1A1LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12610945-B2 Stimuli-responsive polymeric nanoparticles, methods of making stimuli-responsive polymeric nanoparticles, and methods of using stimuli-responsive polymeric nanoparticles UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2026-04-28 US disclosed
US-20230200382-A1 STIMULI-RESPONSIVE POLYMERIC NANOPARTICLES, METHODS OF MAKING STIMULI-RESPONSIVE POLYMERIC NANOPARTICLES, AND METHODS OF USING STIMULI-RESPONSIVE POLYMERIC NANOPARTICLES NATIONAL SCIENCE FOUNDATION 2023-06-29 US disclosed
US-11627738-B2 Stimuli-responsive polymeric nanoparticles, methods of making stimuli-responsive polymeric nanoparticles, and methods of using stimuli-responsive polymeric nanoparticles UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-04-18 US disclosed
US-20220146518-A1 TAG FOR LABELING BIOMOLECULES SHANGHAI POLARIS BIOLOGY CO., LTD. (CN) 2022-05-12 US disclosed
WO-2020228734-A1 A TAG FOR LABELING BIOMOLECULES SHANGHAI POLARIS BIOLOGY CO., LTD. (CN) 2020-11-19 WO disclosed
US-20200352161-A1 STIMULI-RESPONSIVE POLYMERIC NANOPARTICLES, METHODS OF MAKING STIMULI-RESPONSIVE POLYMERIC NANOPARTICLES, AND METHODS OF USING STIMULI-RESPONSIVE POLYMERIC NANOPARTICLES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2020-11-12 US disclosed
WO-2017120098-A1 STIMULI-RESPONSIVE POLYMERIC NANOPARTICLES, METHODS OF MAKING STIMULI-RESPONSIVE POLYMERIC NANOPARTICLES, AND METHODS OF USING STIMULI-RESPONSIVE POLYMERIC NANOPARTICLES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2017-07-13 WO disclosed
US-6670438-B1 Silicatein; polypeptides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220146518-A1 TAG FOR LABELING BIOMOLECULES BTD, DNPEP, ALB EPOR 1080/4885CPB2 470/4885MEN1 2558/4885
US-12610945-B2 Stimuli-responsive polymeric nanoparticles, methods of making stimuli-responsive polymeric nanoparticles, and methods of using stimuli-responsive polymeric nanoparticles CD44, STRAP, PSPH EPOR 1849/4885CPB2 4449/4885MEN1 4045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.