Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CBFB | Q13951 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | TXN | P10599 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1171206 | 0.77 | ALDH1A1 (0.67) | KDM4EHSD17B10ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL14278 | 0.74 | FABP6 (0.59) | KDM4EHSD17B10ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7991998 | 0.74 | KDM4E (0.55) | KDM4EHSD17B10ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL213270 | 0.74 | KDM4E (0.49) | KDM4EHSD17B10ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1193108 | 0.74 | ALDH1A1 (0.49) | KDM4EHSD17B10ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4107335 | 0.74 | HSD17B10 (0.61) | KDM4EHSD17B10ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7214338 | 0.70 | KDM4E (0.43) | KDM4EHSD17B10ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3828091 | 0.69 | OPRL1 (0.60) | KDM4EHSD17B10ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16810842 | 0.69 | TDP1 (0.54) | KDM4EHSD17B10ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL12264335 | 0.69 | GAA (0.62) | KDM4EHSD17B10ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144286-A1 | Benzimidazole derivatives | TULARIK, INC | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144286-A1 | Benzimidazole derivatives | NFATC1, STAT1, IRF3 | KDM4E 924/4885HSD17B10 3670/4885ALDH1A1 1869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.