Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CBFB | Q13951 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12963078 | 0.88 | KDM4E (0.40) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14502996 | 0.84 | MEN1 (0.43) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL211043 | 0.84 | ALDH1A1 (0.44) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL211044 | 0.84 | MAPT (0.49) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18931234 | 0.80 | EIF4A3 (0.41) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8428958 | 0.80 | AMY1A (0.37) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10846976 | 0.79 | MAPT (0.39) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8977368 | 0.77 | OPRL1 (0.37) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9528285 | 0.77 | ATP4A (0.43) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8977372 | 0.77 | GRIA1 (0.35) | KDM4EALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230124700-A1 | OXAZOLE AND THIOAZOLE-TYPE CULLIN RING UBIQUITIN LIGASE COMPOUNDS AND USES THEREOF | CEMM - FORSCHUNGSZENTRUM FÜR MOLEKULARE MEDIZIN GMBH (AT) | 2023-04-20 | — | — | US | disclosed |
| WO-2021074414-A1 | OXAZOLE AND THIOAZOLE-TYPE CULLIN RING UBIQUITIN LIGASE COMPOUNDS AND USES THEREOF | CEMM - FORSCHUNGSZENTRUM FÜR MOLEKULARE MEDIZIN GMBH (AT) | 2021-04-22 | — | — | WO | disclosed |
| US-20160115136-A1 | COMPOUNDS, COMPOSITIONS COMPRSING SAME, AND METHODS RELATED THERETO | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2016-04-28 | — | — | US | disclosed |
| US-8878165-B2 | Electrode treatment process for organic electronic devices | MERCK PATENT GMBH (DE) | 2014-11-04 | — | — | US | disclosed |
| WO-2014160405-A1 | COMPOUNDS, COMPOSITIONS COMPRISING SAME, AND METHODS RELATED THERETO | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2014-10-02 | — | — | WO | disclosed |
| US-8518936-B2 | Method for preparing acid addition salts of polyacidic basic compounds | KOWA CO., LTD. (JP) | 2013-08-27 | — | — | US | disclosed |
| EP-1627875-B1 | METHOD FOR PRODUCING CYCLIC DIAMINE DERIVATIVE OR SALT THEREOF | KOWA CO (JP) | 2013-07-31 | — | — | EP | disclosed |
| US-20120319097-A1 | ELECTRODE TREATMENT PROCESS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-20 | — | — | US | disclosed |
| EP-1642899-B1 | 2,4-BIS(TRIFLUOROETHOXY)PYRIDINE COMPOUND AND MEDICINE CONTAINING THE SAME | KOWA CO (JP) | 2012-08-15 | — | — | EP | disclosed |
| EP-1598346-B1 | PROCESS FOR PRODUCING ACID ADDUCT SALT OF POLYACIDIC BASE COMPOUND | KOWA CO (JP) | 2012-04-18 | — | — | EP | disclosed |
| US-20030083315-A1 | Human chymase inhibitors | TEIJIN LIMITED (JP) | 2003-05-01 | — | — | US | disclosed |
| WO-2003011868-A1 | THIENOPYRIMIDINEDIONES AND THEIR USE IN THE MODULATION OF AUTOIMMUNE DISEASE | ASTRAZENECA AB (SE) | 2003-02-13 | — | — | WO | disclosed |
| EP-1167360-A9 | HUMAN CHYMASE INHIBITORS | TEIJIN LIMITED (JP) | 2002-05-15 | — | — | EP | disclosed |
| EP-1167360-A1 | HUMAN CHYMASE INHIBITORS | TEIJIN LIMITED (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-5922720-A | PHARMACEUTICAL FOR USE IN TREATMENT OF DISEASES BASED ON HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| EP-0772611-A1 | PIPERAZINE THIOPYRIDINES FOR CONTROLLING HELICOBACTER BACTERIA | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996002534-A1 | PIPERAZINE THIOPYRIDINES FOR CONTROLLING HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |
| WO-1996000224-A1 | 4-S- AND N-SUBSTITUTED 6-ALKYLPYRIDINES FOR CONTROLLING HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-01-04 | — | — | WO | disclosed |
| US-4950677-A | ANTIULCER AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1990-08-21 | — | — | US | disclosed |
| EP-0304624-A2 | Benzimidazol-2-yl-pyridinum compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1989-03-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230124700-A1 | OXAZOLE AND THIOAZOLE-TYPE CULLIN RING UBIQUITIN LIGASE COMPOUNDS AND USES THEREOF | CUL1, CUL5, CUL3 | KDM4E 1471/4885ALDH1A1 1348/4885CYP1A2 1442/4885 |
| US-20160115136-A1 | COMPOUNDS, COMPOSITIONS COMPRSING SAME, AND METHODS RELATED THERETO | LPO, NOTUM, FARS2 | KDM4E 2304/4885ALDH1A1 1503/4885CYP1A2 230/4885 |
| US-20030083315-A1 | Human chymase inhibitors | CMA1, CTRL, CPA4 | KDM4E 588/4885ALDH1A1 687/4885CYP1A2 528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.