Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.52 |
| ▸ | MMP3 | P08254 | 7/20 | 0.52 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
| ▸ | MMP14 | P50281 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 5/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964787 | 0.89 | MMP2 (0.52) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6437469 | 0.88 | MMP2 (0.63) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6433636 | 0.86 | MMP2 (0.55) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6586377 | 0.85 | MMP2 (0.51) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6433435 | 0.85 | MMP2 (0.52) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6435026 | 0.84 | MMP2 (0.51) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6964268 | 0.84 | MMP2 (0.53) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6434175 | 0.83 | MMP2 (0.54) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6434246 | 0.83 | MMP2 (0.51) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6434243 | 0.83 | MMP2 (0.51) | MMP2MMP3MMP1MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181017-B1 | METALLOPROTEASE INHIBITORS | PFIZER LTD (GB) | 2003-04-16 | — | — | EP | claimed |