Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7125372 | 0.82 | — | — | |
| SCHEMBL7129769 | 0.79 | TSHR (0.42) | ALDH1A1 | |
| SCHEMBL7132599 | 0.78 | EPHX2 (0.38) | ALDH1A1LMNATHRBHTTSMN1; SMN2 | |
| SCHEMBL23827187 | 0.77 | NPSR1 (0.36) | ALDH1A1LMNATHRBHTTSMN1; SMN2 | |
| SCHEMBL7797408 | 0.76 | NPSR1 (0.46) | ALDH1A1LMNATHRBHTTSMN1; SMN2 | |
| SCHEMBL7125107 | 0.76 | ALDH1A1 (0.32) | ALDH1A1LMNATHRBHTTSMN1; SMN2 | |
| SCHEMBL1818541 | 0.69 | TSHR (0.39) | — | |
| SCHEMBL10228479 | 0.68 | HSD11B1 (0.36) | ALDH1A1THRB | |
| SCHEMBL28512066 | 0.67 | NPSR1 (0.31) | — | |
| SCHEMBL1337900 | 0.67 | NPSR1 (0.42) | ALDH1A1LMNATHRBHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670499-B1 | Bis-Methacryloyloxy-adamantanedicarboxylate derivatives; raw materials for dental materials and lenses; transparency, luster, hardness, water resistance | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-12-30 | — | — | US | disclosed |