SCHEMBL7129795

SCHEMBL7129795

O=C(Cc1ccccc1)c1ccccc1C(=O)Cc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
CES1 P23141 2/20 0.61
CES2 O00748 1/20 0.61
AKR1B1 P15121 1/20 0.61
USP2 O75604 1/20 0.59
TP53 P04637 1/20 0.59
L3MBTL1 Q9Y468 2/20 0.55
MAPT P10636 1/20 0.55
SRD5A2 P31213 2/20 0.53
LMNA P02545 1/20 0.53
HDAC8 Q9BY41 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
FNTA P49354 1/20 0.50
FNTB P49356 1/20 0.50
ALDH1A1 P00352 2/20 0.48
MAPK1 P28482 1/20 0.48
CTBP2 P56545 1/20 0.48
EPHX2 P34913 1/20 0.48
ALOX15 P16050 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1787541 0.93 USP2 (0.69) MEN1KMT2ACES1CES2AKR1B1
SCHEMBL28705224 0.89 USP2 (0.56) MEN1KMT2ACES1CES2AKR1B1
SCHEMBL27982504 0.88 CES1 (0.54) MEN1KMT2ACES1CES2AKR1B1
SCHEMBL29586388 0.87 HPGD (0.56) MEN1KMT2ACES1CES2AKR1B1
SCHEMBL8376 0.87 HPGD (0.56) MEN1KMT2ACES1CES2AKR1B1
SCHEMBL1515738 0.85 SMN1; SMN2 (0.60) MEN1KMT2ACES1CES2AKR1B1
SCHEMBL1515749 0.85 PTPN1 (0.59) MEN1KMT2ACES1CES2AKR1B1
SCHEMBL3244289 0.85 USP2 (0.51) MEN1KMT2ACES1CES2AKR1B1
SCHEMBL4175858 0.85 KDM4E (0.56) MEN1KMT2ACES1CES2AKR1B1
SCHEMBL30394799 0.85 SMN1; SMN2 (0.60) MEN1KMT2ACES1CES2AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003042148-A2 PROCESS FOR PRODUCING BISBENZIL COMPOUNDS SHOWA DENKO K. K. (JP) 2003-05-22 WO claimed
WO-2003042148-A3 PROCESS FOR PRODUCING BISBENZIL COMPOUNDS SHOWA DENKO KK (JP) 2003-10-16 WO disclosed
JP-2003192629-A METHOD FOR PRODUCING BIS(PHENYLACETYL)BENZENE SHOWA DENKO KK 2003-07-09 JP disclosed
JP-2003192628-A METHOD FOR PRODUCING BISBENZYL COMPOUND SHOWA DENKO KK 2003-07-09 JP disclosed
JP-2003171332-A METHOD FOR PRODUCING BISBENZYL COMPOUND SHOWA DENKO KK 2003-06-20 JP disclosed
WO-2003042148-A2 PROCESS FOR PRODUCING BISBENZIL COMPOUNDS SHOWA DENKO K. K. (JP) 2003-05-22 WO disclosed
WO-2003042148-A2 PROCESS FOR PRODUCING BISBENZIL COMPOUNDS SHOWA DENKO K. K. (JP) 2003-05-22 WO disclosed
US-3935239-A Process for producing aromatic α-diketones NEILAND OYAR YANOVICH 1976-01-27 US disclosed