Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129795 | 0.93 | MEN1 (0.62) | USP2TP53ALDH1A1ALOX15KMT2A | |
| SCHEMBL7663868 | 0.87 | USP2 (0.64) | USP2TP53ALDH1A1ALOX15KMT2A | |
| SCHEMBL7811204 | 0.87 | TP53 (0.64) | USP2TP53ALDH1A1ALOX15KMT2A | |
| SCHEMBL29351857 | 0.87 | USP2 (0.64) | USP2TP53ALDH1A1ALOX15KMT2A | |
| Phthalic Acid SCHEMBL10781202 | 0.84 | AKR1B1 (0.77) | USP2TP53ALDH1A1ALOX15KMT2A | |
| SCHEMBL1358285 | 0.84 | ALDH1A1 (0.59) | USP2TP53ALDH1A1ALOX15KMT2A | |
| SCHEMBL1689462 | 0.84 | FOLH1 (0.54) | USP2TP53ALDH1A1ALOX15KMT2A | |
| SCHEMBL3244289 | 0.83 | USP2 (0.51) | USP2TP53ALDH1A1ALOX15KMT2A | |
| SCHEMBL28705224 | 0.83 | USP2 (0.56) | USP2TP53ALDH1A1KMT2AMEN1 | |
| SCHEMBL10954405 | 0.83 | G6PD (0.52) | USP2TP53ALDH1A1ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004235-B | Stereoselective synthesis method of (Z) -3-alkenylphthalide derivative | 中国医学科学院药物研究所 | 2023-05-05 | — | — | CN | disclosed |
| CN-115197565-A | Semi-crystalline polyamide composition based on short diamines with high glass transition temperature, method for the production thereof and use thereof | 阿科玛法国公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-110446740-B | Semi-crystalline polyamide compositions based on short diamines with high glass transition temperature, method for the production thereof and use thereof | 阿科玛法国公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-110431169-B | Semi-crystalline polyamide composition having a high glass transition temperature and a high melting temperature, method for preparing same and use thereof | 阿科玛法国公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-113004235-A | Stereoselective synthesis method of (Z) -3-alkenyl phthalide derivative | 中国医学科学院药物研究所 | 2021-06-22 | — | — | CN | disclosed |
| CN-107949596-B | Semi-crystalline polyamide component with high glass transition temperature for composite materials, method for the production thereof and use thereof | 阿科玛法国公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-108026267-B | Semi-crystalline polyamide composition with high glass transition temperature for thermoplastic materials, method for the production thereof and use thereof | 阿科玛法国公司 | 2021-02-02 | — | — | CN | disclosed |
| US-20170112843-A1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | THE SCRIPPS RESEARCH INSTITUTE | 2017-04-27 | — | — | US | disclosed |
| US-9464065-B2 | Compounds and methods for inducing chondrogenesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-10-11 | — | — | US | disclosed |
| US-8859549-B2 | Potassium channel modulators | ABBVIE, INC. (US) | 2014-10-14 | — | — | US | disclosed |
| US-5624922-A | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0597540-B1 | Aryl-fused and hetaryl-fused-2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC (US) | 1996-06-05 | — | — | EP | disclosed |
| US-5380721-A | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0597540-A1 | Aryl-fused and hetaryl-fused-2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1994-05-18 | — | — | EP | disclosed |
| US-5268372-A | Where nitrogen in position 2 and 5 are connected by a methylene bridge | STERLING WINTHROP INC. (US) | 1993-12-07 | — | — | US | disclosed |
| US-5206231-A | 2,5-benzodiazocine antiarrhythmic agents | STERLING DRUG INC. (US) | 1993-04-27 | — | — | US | disclosed |
| EP-0475527-A2 | Aryl-fused and hetaryl-fused-2, 4-diazepine and 2, 4-diazocine antiarrhythmic agents | STERLING DRUG INC. (US) | 1992-03-18 | — | — | EP | disclosed |
| US-4841047-A | ANTIALLERGENS | AASTA PHARMA AG (DE) | 1989-06-20 | — | — | US | disclosed |
| US-4058529-A | Polycyclic amino derivatives of pyrrolidone and piperidone | CIBA-GEIGY CORPORATION (US) | 1977-11-15 | — | — | US | disclosed |
| US-3994920-A | APPETITE SUPPRESSANT, ANTIDEPRESSANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170112843-A1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | COL2A1, BMP4, BMP2 | USP2 1657/4885TP53 816/4885ALDH1A1 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.