Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 15/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834037 | 0.77 | PHGDH (0.52) | PHGDH | |
| SCHEMBL2792109 | 0.77 | PHGDH (0.61) | PHGDHPTPN1PIN1 | |
| SCHEMBL4692583 | 0.76 | PTPN1 (0.52) | PHGDHPTPN1 | |
| SCHEMBL4692622 | 0.75 | RXFP1 (0.47) | PHGDHPTPN1 | |
| SCHEMBL6830131 | 0.70 | ALDH1A1 (0.54) | PHGDH | |
| SCHEMBL13078329 | 0.70 | PHGDH (0.59) | PHGDHPIN1 | |
| SCHEMBL2678185 | 0.69 | PHGDH (0.60) | PHGDHPTPN1PIN1 | |
| SCHEMBL2790174 | 0.69 | PHGDH (0.58) | PHGDHPIN1 | |
| SCHEMBL4298598 | 0.67 | PHGDH (0.59) | PHGDHPIN1 | |
| SCHEMBL13044184 | 0.67 | PHGDH (0.63) | PHGDHPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |