Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830131 | 0.90 | ALDH1A1 (0.54) | PHGDHALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL6833810 | 0.85 | AKR1C2 (0.48) | MEN1POLBKMT2AAKR1C4AKR1C3 | |
| SCHEMBL6833786 | 0.80 | GRM5 (0.55) | ALDH1A1MEN1POLBHPGDKMT2A | |
| SCHEMBL7129937 | 0.77 | PHGDH (0.44) | PHGDH | |
| SCHEMBL6814323 | 0.75 | SNCA (0.59) | ALDH1A1KDM4EPOLBAKR1C4AKR1C3 | |
| SCHEMBL6835781 | 0.74 | MCL1 (0.55) | PHGDHMEN1LMNAKMT2AAKR1C4 | |
| SCHEMBL2792109 | 0.74 | PHGDH (0.61) | PHGDH | |
| SCHEMBL6353351 | 0.74 | SERPINE1 (0.71) | MEN1KMT2AAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL6830501 | 0.74 | KMT2A (0.76) | ALDH1A1KDM4EMEN1LMNAPOLB | |
| SCHEMBL28838817 | 0.74 | HDAC3 (0.53) | PHGDHALDH1A1KDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | PHGDH 1531/4885ALDH1A1 170/4885KDM4E 1240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.