Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7132580 | 1.00 | TSHR (0.47) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7121885 | 0.99 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7129270 | 0.95 | TSHR (0.42) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7125425 | 0.89 | THRB (0.38) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7132587 | 0.81 | TSHR (0.48) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7120784 | 0.81 | TSHR (0.48) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL18822998 | 0.80 | TSHR (0.53) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7797293 | 0.75 | NPSR1 (0.55) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7797332 | 0.75 | NPSR1 (0.55) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7129749 | 0.74 | TSHR (0.43) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670499-B1 | Bis-Methacryloyloxy-adamantanedicarboxylate derivatives; raw materials for dental materials and lenses; transparency, luster, hardness, water resistance | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-12-30 | — | — | US | disclosed |