Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7121885 | 0.96 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7130202 | 0.95 | TSHR (0.47) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7132580 | 0.95 | TSHR (0.47) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7125425 | 0.92 | THRB (0.38) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7132426 | 0.76 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL7129749 | 0.76 | TSHR (0.43) | TSHRALDH1A1 | |
| SCHEMBL7120784 | 0.75 | TSHR (0.48) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7132587 | 0.75 | TSHR (0.48) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL18822998 | 0.73 | TSHR (0.53) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7125323 | 0.73 | TSHR (0.45) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670499-B1 | Bis-Methacryloyloxy-adamantanedicarboxylate derivatives; raw materials for dental materials and lenses; transparency, luster, hardness, water resistance | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-12-30 | — | — | US | disclosed |