Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.42 |
| ▸ | KDM5A | P29375 | 5/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27486524 | 1.00 | S1PR2 (0.50) | S1PR2S1PR1S1PR3S1PR5GGPS1 | |
| SCHEMBL27504205 | 1.00 | S1PR2 (0.50) | S1PR2S1PR1S1PR3S1PR5GGPS1 | |
| SCHEMBL625083 | 1.00 | S1PR2 (0.50) | S1PR2S1PR1S1PR3S1PR5GGPS1 | |
| SCHEMBL6402048 | 0.98 | S1PR2 (0.47) | S1PR2S1PR1S1PR3S1PR5GGPS1 | |
| SCHEMBL22861284 | 0.98 | S1PR2 (0.52) | S1PR2S1PR1S1PR3S1PR5GGPS1 | |
| SCHEMBL28875752 | 0.98 | S1PR2 (0.52) | S1PR2S1PR1S1PR3S1PR5GGPS1 | |
| SCHEMBL7109405 | 0.98 | S1PR2 (0.52) | S1PR2S1PR1S1PR3S1PR5GGPS1 | |
| SCHEMBL20495919 | 0.98 | S1PR2 (0.52) | S1PR2S1PR1S1PR3S1PR5GGPS1 | |
| SCHEMBL5430321 | 0.98 | S1PR2 (0.52) | S1PR2S1PR1S1PR3S1PR5GGPS1 | |
| SCHEMBL2925349 | 0.98 | S1PR2 (0.52) | S1PR2S1PR1S1PR3S1PR5GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3578161-B1 | METHOD FOR IMPROVING STORAGE STABILITY OF COSMETIC | ADEKA CORP (JP) | 2025-11-12 | — | — | EP | disclosed |
| US-20220249354-A1 | WATER BASED COMPOSITION | SHISEIDO COMPANY, LTD. (JP) | 2022-08-11 | — | — | US | disclosed |
| WO-2022138425-A1 | WATER-IN-OIL TYPE EMULSION COSMETIC | 株式会社 資生堂 | 2022-06-30 | — | — | WO | disclosed |
| WO-2021106874-A1 | SKIN CLEANSING AGENT | 花王株式会社 | 2021-06-03 | — | — | WO | disclosed |
| WO-2020230356-A1 | GEL CLEANING AGENT | 資生堂ホネケーキ工業株式会社 | 2020-11-19 | — | — | WO | disclosed |
| EP-3578161-A1 | METHOD FOR IMPROVING STORAGE STABILITY OF COSMETIC | Adeka Corporation (JP) | 2019-12-11 | — | — | EP | disclosed |
| US-10307366-B2 | Composition and related method for inhibiting moisture loss from skin | ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) | 2019-06-04 | — | — | US | disclosed |
| US-20190160117-A1 | METHOD AND TOPICAL COMPOSITION FOR MODIFICATION OF A SKIN MICROBIOME | ACCESS BUSINESS GROUP INTERNATIONAL LLC | 2019-05-30 | — | — | US | disclosed |
| US-20170252293-A1 | COMPOSITION AND RELATED METHOD FOR INHIBITING MOISTURE LOSS FROM SKIN | ACCESS BUSINESS GROUP INTERNATIONAL LLC | 2017-09-07 | — | — | US | disclosed |
| EP-1688126-B1 | GLYCYLGLYCINE AS PARAKERATOSIS INHIBITOR | SHISEIDO CO LTD (JP) | 2017-08-23 | — | — | EP | disclosed |
| EP-1541633-A1 | AQUEOUS SUSPENSION OF CROSSLINKED SILICONE PARTICLES, AQUEOUS EMULSION OF OIL CONTAINING CROSSLINKED SILICONE PARTICLES, AND COSMETIC INGREDIENTS | Dow Corning Toray Silicone Company, Ltd. (JP) | 2005-06-15 | — | — | EP | disclosed |
| EP-0797984-B1 | Anti-aging cosmetic composition | SHISEIDO CO LTD (JP) | 2005-02-16 | — | — | EP | disclosed |
| WO-2004084646-A2 | COSMETIC COMPOSITIONS COMPRISING PHYTOSTEROL ESTERS | ENZYMOTEC LTD. (IL) | 2004-10-07 | — | — | WO | disclosed |
| EP-0815838-B1 | External skin treatment composition | SHISEIDO CO LTD (JP) | 2004-04-28 | — | — | EP | disclosed |
| US-6419962-B1 | PLANT EXTRACT IN CARRIER | SHISEIDO COMPANY, LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| US-20020041889-A1 | ENHANCING AGENT FOR DEGRADATION OF DESMOSOMES OR STRATUM CORNEUM DESQUAMATION | SHISEIDO COMPANY, LTD. (JP) | 2002-04-11 | — | — | US | disclosed |
| US-5853705-A | Anti-aging cosmetic composition | SHISEIDO COMPANY, LTD. (JP) | 1998-12-29 | — | — | US | disclosed |
| EP-0852949-A2 | Use of alpha-amino-acids for enhancing desmosomal degradation or stratum corneum desquamation | SHISEIDO COMPANY LIMITED (JP) | 1998-07-15 | — | — | EP | disclosed |
| EP-0815838-A2 | External skin treatment composition | SHISEIDO COMPANY, LTD. (JP) | 1998-01-07 | — | — | EP | disclosed |
| EP-0797984-A2 | Anti-aging cosmetic composition | SHISEIDO COMPANY LIMITED (JP) | 1997-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020041889-A1 | ENHANCING AGENT FOR DEGRADATION OF DESMOSOMES OR STRATUM CORNEUM DESQUAMATION | DSG1, DSC1, CUTA | S1PR2 4031/4885S1PR1 3170/4885S1PR3 3698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.