Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581315 | 0.84 | MEN1 (0.63) | BCL2MCL1MAPTMEN1KMT2A | |
| SCHEMBL30397720 | 0.78 | ALDH1A1 (0.55) | HDAC4HDAC2HDAC8HDAC6BCL2 | |
| SCHEMBL1980808 | 0.78 | ALDH1A1 (0.55) | HDAC4HDAC2HDAC8HDAC6BCL2 | |
| SCHEMBL3194696 | 0.76 | MAPT (0.62) | BCL2MCL1MAPTMEN1KMT2A | |
| SCHEMBL899150 | 0.76 | MEN1 (0.68) | BCL2MCL1MAPTMEN1KMT2A | |
| SCHEMBL11786814 | 0.74 | HDAC4 (0.54) | HDAC4HDAC2HDAC8HDAC6MAPT | |
| SCHEMBL4598394 | 0.73 | PDE4B (0.56) | HDAC4HDAC2HDAC8HDAC6MAPT | |
| SCHEMBL476897 | 0.72 | MEN1 (0.57) | HDAC4HDAC2HDAC8HDAC6BCL2 | |
| SCHEMBL31185666 | 0.72 | MEN1 (0.57) | HDAC4HDAC2HDAC8HDAC6BCL2 | |
| SCHEMBL18068454 | 0.71 | KDM4E (0.46) | HDAC4HDAC2HDAC8HDAC6BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968203-B1 | PHOTOACTIVE COUMARIN SULFONATE COMPOUNDS | CLARIANT FINANCE BVI LTD (VG) | 2003-06-11 | — | — | EP | claimed |
| CN-1251585-A | Photoactive coumarin sulfonate compound | CELANESE HOECHST INTERNATIONAL (CH) | 2000-04-26 | — | — | CN | claimed |
| EP-0968203-A1 | PHOTOACTIVE COUMARIN SULFONATE COMPOUNDS | CLARIANT INTERNATIONAL LTD. (CH) | 2000-01-05 | — | — | EP | claimed |
| WO-1998039320-A1 | PHOTOACTIVE COUMARIN SULFONATE COMPOUNDS | CLARIANT INTERNATIONAL LTD. (CH) | 1998-09-11 | — | — | WO | claimed |
| US-5739295-A | SULFONYL HALIDE OR SULFONIC ACID ESTERS OF 3-DIAZO-2,4-DIOXO-BENZOHETERCYCLIC COMPOUNDS USEFUL SYNTHETIC INTERMEDIATES FOR PHOTORESISTS, OPTOELECTRONICS, AGRICULTURE AND DRUGS | HOECHST CELANESE CORPORATION (US) | 1998-04-14 | — | — | US | claimed |
| EP-0980364-B1 | Process for preparing coumarin sulphonates | CLARIANT FINANCE BVI LTD (VG) | 2003-07-02 | — | — | EP | disclosed |
| EP-0968203-B1 | PHOTOACTIVE COUMARIN SULFONATE COMPOUNDS | CLARIANT FINANCE BVI LTD (VG) | 2003-06-11 | — | — | EP | disclosed |
| CN-1251585-A | Photoactive coumarin sulfonate compound | CELANESE HOECHST INTERNATIONAL (CH) | 2000-04-26 | — | — | CN | disclosed |
| EP-0980364-A1 | PROCESS FOR PREPARING COUMARIN SULFONATES | Clariant International Ltd. (CH) | 2000-02-23 | — | — | EP | disclosed |
| EP-0968203-A1 | PHOTOACTIVE COUMARIN SULFONATE COMPOUNDS | CLARIANT INTERNATIONAL LTD. (CH) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998039320-A1 | PHOTOACTIVE COUMARIN SULFONATE COMPOUNDS | CLARIANT INTERNATIONAL LTD. (CH) | 1998-09-11 | — | — | WO | disclosed |
| WO-1998039318-A1 | PROCESS FOR PREPARING COUMARIN SULFONATES | CLARIANT INTERNATIONAL LTD. (CH) | 1998-09-11 | — | — | WO | disclosed |
| US-5773591-A | PHOTORESISTS, LIGHT SENSITIVE ELEMENTS AND DIAZO RESINS | HOECHST CELANESE CORP. (US) | 1998-06-30 | — | — | US | disclosed |
| US-5739295-A | SULFONYL HALIDE OR SULFONIC ACID ESTERS OF 3-DIAZO-2,4-DIOXO-BENZOHETERCYCLIC COMPOUNDS USEFUL SYNTHETIC INTERMEDIATES FOR PHOTORESISTS, OPTOELECTRONICS, AGRICULTURE AND DRUGS | HOECHST CELANESE CORPORATION (US) | 1998-04-14 | — | — | US | disclosed |