Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KIT | P10721 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | LDHA | P00338 | 2/20 | 0.48 |
| ▸ | LCK | P06239 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16307608 | 0.90 | MAP4K4 (0.59) | EPHX2NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6093198 | 0.87 | EPHX2 (0.51) | EPHX2NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL14079744 | 0.86 | LDHA (0.67) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2055274 | 0.86 | LCK (0.52) | NPC1RAB9AMAPTSMN1; SMN2MAP4K4 | |
| SCHEMBL30554092 | 0.82 | LDHA (0.46) | NPC1RAB9AMAPTMAP4K4LDHA | |
| SCHEMBL20868778 | 0.82 | LDHA (0.46) | NPC1RAB9AMAPTMAP4K4LDHA | |
| SCHEMBL558100 | 0.81 | LDHA (0.71) | EPHX2NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL30554089 | 0.80 | LCK (0.45) | EPHX2NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL210096 | 0.79 | NPC1 (0.61) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24104135 | 0.79 | EPHX2 (0.68) | EPHX2NPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030134859-A1 | PPAR-gamma modulator | SANKYO COMPANY, LIMITED (JP) | 2003-07-17 | — | — | US | disclosed |
| EP-1277729-A1 | PPAR (GAMMA) MODULATORS | Sankyo Company, Limited (JP) | 2003-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134859-A1 | PPAR-gamma modulator | PPARG, PPARA, PPARD | EPHX2 3491/4885NPC1 1152/4885RAB9A 1179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.