Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6924525 | 0.82 | LMNA (0.56) | LMNAAKR1B10AKR1B1KMT2AMEN1 | |
| SCHEMBL6924526 | 0.82 | LMNA (0.56) | LMNAAKR1B10AKR1B1KMT2AMEN1 | |
| SCHEMBL7108321 | 0.81 | LMNA (0.52) | LMNAAKR1B10AKR1B1KMT2AMEN1 | |
| SCHEMBL29010570 | 0.79 | LMNA (0.51) | LMNAAKR1B10AKR1B1KMT2AMEN1 | |
| SCHEMBL28249422 | 0.77 | LMNA (0.51) | LMNAAKR1B10AKR1B1KMT2AMEN1 | |
| SCHEMBL28730448 | 0.77 | LMNA (0.61) | LMNAAKR1B10AKR1B1KMT2AMEN1 | |
| Isobutyl Cinnamate SCHEMBL28250183 | 0.76 | LMNA (0.50) | LMNAAKR1B10AKR1B1KMT2AMEN1 | |
| SCHEMBL7109640 | 0.76 | NPC1 (0.43) | LMNAAKR1B10AKR1B1ALDH1A1RAB9A | |
| Phenethyl Cinnamate SCHEMBL28250131 | 0.75 | AKR1B10 (0.77) | LMNAAKR1B10AKR1B1KMT2AMEN1 | |
| Allyl Cinnamate SCHEMBL27652867 | 0.75 | APP (0.50) | LMNAAKR1B10AKR1B1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6667341-B2 | Amidomethyl esters, carbonylmercaptomethyl esters, keto-containing esters, amidomethyl thioesters, amidomethyl amides, and methylene dithioesters; anticancer agents, hemological disorders, and inherited metabolic disorders | BEACON LABORATORIES, INC. | 2003-12-23 | — | — | US | disclosed |
| US-6562995-B1 | Amidomethyl esters, carbonylmercaptomethyl esters, keto-containing esters, amidomethyl thioesters, amidomethyl amides, and methylene dithioesters are disclosed. The novel compounds have two carbonyl groups connected by a linking moiety having | BEACON LABORATORIES, INC. | 2003-05-13 | — | — | US | disclosed |
| EP-1216986-A2 | Novel delta dicarbonyl compounds and methods for using same | Beacon Laboratories, Inc. (US) | 2002-06-26 | — | — | EP | disclosed |