Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.55 |
| ▸ | MGAT2 | Q10469 | 3/20 | 0.52 |
| ▸ | GSK3B | P49841 | 3/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5357745 | 0.94 | MOGAT2 (0.58) | MOGAT2MGAT2GSK3BPRKDCLRRK2 | |
| SCHEMBL5358368 | 0.93 | MOGAT2 (0.61) | MOGAT2MGAT2GSK3BLRRK2 | |
| SCHEMBL7133915 | 0.90 | PGR (0.54) | MOGAT2MGAT2GSK3BPRKDCLRRK2 | |
| SCHEMBL5370221 | 0.89 | MOGAT2 (0.57) | MOGAT2MGAT2 | |
| SCHEMBL5361301 | 0.89 | MOGAT2 (0.56) | MOGAT2MGAT2GSK3BLRRK2 | |
| SCHEMBL5361465 | 0.89 | MOGAT2 (0.59) | MOGAT2MGAT2GSK3BPRKDCLRRK2 | |
| SCHEMBL5362785 | 0.89 | MOGAT2 (0.56) | MOGAT2MGAT2 | |
| SCHEMBL5359548 | 0.88 | MOGAT2 (0.54) | MOGAT2MGAT2GSK3BPRKDC | |
| SCHEMBL5362279 | 0.87 | MOGAT2 (0.57) | MOGAT2MGAT2PRKDC | |
| SCHEMBL7139382 | 0.87 | AR (0.64) | MOGAT2MGAT2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506763-B2 | Useful in prevention and treatment of protein kinase related disorders such as cancer | SUGEN, INC. | 2003-01-14 | — | — | US | disclosed |