SCHEMBL7133137

SCHEMBL7133137

C=CC(=O)C(O)CCCN

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 3/20 0.36
GSR P00390 1/20 0.34
RNPEP Q9H4A4 1/20 0.33
TSHR P16473 2/20 0.31
GABRR3 A8MPY1 1/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
HDAC3 O15379 1/20 0.31
GABBR2 O75899 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
THRB P10828 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRR1 P24046 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRR2 P28476 1/20 0.31
SLC6A1 P30531 1/20 0.31
GABRA5 P31644 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6130406 0.86
SCHEMBL3626773 0.80 GPR84 (0.30)
SCHEMBL28091019 0.80 GPR84 (0.30)
SCHEMBL5935196 0.78 GPR84 (0.47) TSHR
Ammonia Solution, Strong SCHEMBL28187259 0.78
SCHEMBL10758579 0.77 ABCC4 (0.42) TSHRLMNABLMKMT2ACYP2D6
SCHEMBL17335978 0.77 CPB2 (0.44) CPB2GSRRNPEPTSHRGABRR3
Ammonia Solution, Strong SCHEMBL28187902 0.77 GPR84 (0.32)
SCHEMBL588667 0.77
SCHEMBL27670579 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0880693-B1 USE OF MULTIPLE GRADIENTS IN ELECTROPHORESIS IN GEL SLABS AND IN CAPILLARIES RIGHETTI PIER GIORGIO (IT) 2003-07-09 EP claimed
EP-0880693-A1 USE OF MULTIPLE GRADIENTS IN ELECTROPHORESIS IN GEL SLABS AND IN CAPILLARIES RIGHETTI, Pier Giorgio (IT) 1998-12-02 EP claimed
WO-1997030346-A1 CREATION AND USE OF MULTIPLE GRADIENTS IN ELECTROPHORESIS IN GEL SLABS AND IN CAPILLARIES RIGHETTI PIER GIORGIO (IT) 1997-08-21 WO claimed