Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 7/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 4/20 | 0.42 |
| ▸ | PLA2G2E | Q9NZK7 | 3/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 3/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6842022 | 0.86 | BCAT2 (0.63) | FOLH1BCAT2KMT2ADPP4FGFR1 | |
| Bicarbonate SCHEMBL1839603 | 0.84 | KMT2A (0.60) | FOLH1BCAT2KMT2ADPP4PDCD1 | |
| Acetic Acid SCHEMBL8749452 | 0.82 | KMT2A (0.58) | FOLH1BCAT2KMT2ADPP4PDCD1 | |
| SCHEMBL31261742 | 0.82 | DPP4 (0.60) | FOLH1KMT2ADPP4PDCD1CD274 | |
| SCHEMBL328862 | 0.82 | DPP4 (0.60) | FOLH1KMT2ADPP4PDCD1CD274 | |
| SCHEMBL25181448 | 0.81 | FOLH1 (0.68) | FOLH1KMT2ADPP4PDCD1CD274 | |
| Bicarbonate SCHEMBL1836698 | 0.80 | KMT2A (0.52) | FOLH1BCAT2KMT2ADPP4PDCD1 | |
| SCHEMBL28147534 | 0.80 | FOLH1 (0.50) | FOLH1BCAT2KMT2ADPP4PDCD1 | |
| SCHEMBL28790583 | 0.80 | KMT2A (0.55) | FOLH1BCAT2KMT2ADPP4PDCD1 | |
| Water SCHEMBL9719797 | 0.80 | DPP4 (0.58) | FOLH1KMT2ADPP4PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |