Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 13/20 | 0.63 |
| ▸ | LCK | P06239 | 11/20 | 0.63 |
| ▸ | TEK | Q02763 | 7/20 | 0.63 |
| ▸ | KDR | P35968 | 4/20 | 0.63 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.63 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.63 |
| ▸ | ABL1 | P00519 | 9/20 | 0.53 |
| ▸ | PTK6 | Q13882 | 8/20 | 0.52 |
| ▸ | FYN | P06241 | 3/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | FRK | P42685 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.48 |
| ▸ | YES1 | P07947 | 2/20 | 0.47 |
| ▸ | LYN | P07948 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5801455 | 0.92 | SRC (0.59) | SRCLCKTEKKDRLIMK1 | |
| SCHEMBL5821267 | 0.90 | SRC (0.58) | SRCLCKTEKKDRLIMK1 | |
| SCHEMBL7142801 | 0.86 | SRC (0.51) | SRCLCKTEKKDRLIMK1 | |
| SCHEMBL7138358 | 0.84 | ABL1 (0.52) | SRCLCKKDRABL1PTK6 | |
| SCHEMBL5802027 | 0.79 | SRC (0.54) | SRCLCKTEKKDRABL1 | |
| SCHEMBL6692919 | 0.78 | SRC (0.45) | SRCLCKTEKKDRLIMK1 | |
| SCHEMBL5805157 | 0.77 | LCK (1.00) | SRCLCKTEKKDRLIMK1 | |
| SCHEMBL6645184 | 0.77 | LCK (1.00) | SRCLCKTEKKDRLIMK1 | |
| SCHEMBL6431442 | 0.77 | SRC (0.49) | SRCLCKTEKKDRLIMK1 | |
| Hydrochloric Acid SCHEMBL6431443 | 0.76 | SRC (0.49) | SRCLCKTEKKDRLIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660744-B1 | Kinase inhibitors | ABBOTT GMBH & CO. KG (DE) | 2003-12-09 | — | — | US | disclosed |