Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 17/20 | 0.52 |
| ▸ | SRC | P12931 | 15/20 | 0.52 |
| ▸ | HCK | P08631 | 13/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.52 |
| ▸ | EGFR | P00533 | 10/20 | 0.52 |
| ▸ | KDR | P35968 | 10/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 10/20 | 0.52 |
| ▸ | MTOR | P42345 | 10/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.52 |
| ▸ | EPHB4 | P54760 | 10/20 | 0.52 |
| ▸ | PRKDC | P78527 | 10/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 8/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.51 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.51 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.46 |
| ▸ | PTK6 | Q13882 | 6/20 | 0.46 |
| ▸ | FYN | P06241 | 3/20 | 0.45 |
| ▸ | LCK | P06239 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5823902 | 0.90 | ABL1 (0.54) | ABL1SRCHCKPIK3CDEGFR | |
| SCHEMBL7133248 | 0.84 | SRC (0.63) | ABL1SRCHCKPIK3CDEGFR | |
| SCHEMBL7142801 | 0.83 | SRC (0.51) | ABL1SRCHCKPIK3CDEGFR | |
| SCHEMBL27604491 | 0.79 | SRC (0.76) | ABL1SRCHCKPIK3CDEGFR | |
| SCHEMBL5823904 | 0.77 | CFTR (0.45) | ABL1SRCHCKPIK3CDEGFR | |
| SCHEMBL5801455 | 0.76 | SRC (0.59) | ABL1SRCHCKPIK3CDEGFR | |
| SCHEMBL7167170 | 0.76 | JAK2 (0.42) | SRCPIK3CDEGFRKDRFYN | |
| SCHEMBL5802027 | 0.76 | SRC (0.54) | ABL1SRCHCKPIK3CDEGFR | |
| SCHEMBL6431442 | 0.75 | SRC (0.49) | ABL1SRCHCKPIK3CDEGFR | |
| Hydrochloric Acid SCHEMBL6431443 | 0.74 | SRC (0.49) | ABL1SRCHCKPIK3CDEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1520298-A | Pyrazolopyrimidines as therapeutic agents | �����ʩ���عɷݹ�˾ | 2004-08-11 | — | — | CN | disclosed |
| US-6660744-B1 | Kinase inhibitors | ABBOTT GMBH & CO. KG (DE) | 2003-12-09 | — | — | US | disclosed |