Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 13/20 | 0.51 |
| ▸ | LCK | P06239 | 10/20 | 0.51 |
| ▸ | TEK | Q02763 | 7/20 | 0.51 |
| ▸ | ABL1 | P00519 | 9/20 | 0.49 |
| ▸ | PTK6 | Q13882 | 8/20 | 0.48 |
| ▸ | FYN | P06241 | 3/20 | 0.47 |
| ▸ | YES1 | P07947 | 2/20 | 0.47 |
| ▸ | LYN | P07948 | 2/20 | 0.47 |
| ▸ | HCK | P08631 | 2/20 | 0.47 |
| ▸ | FGR | P09769 | 2/20 | 0.47 |
| ▸ | BLK | P51451 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 4/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.46 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | FRK | P42685 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5802027 | 0.92 | SRC (0.54) | SRCLCKTEKABL1PTK6 | |
| SCHEMBL6431442 | 0.91 | SRC (0.49) | SRCLCKTEKABL1PTK6 | |
| Hydrochloric Acid SCHEMBL6431443 | 0.91 | SRC (0.49) | SRCLCKTEKABL1PTK6 | |
| SCHEMBL7133248 | 0.86 | SRC (0.63) | SRCLCKTEKABL1PTK6 | |
| SCHEMBL7138358 | 0.83 | ABL1 (0.52) | SRCLCKABL1PTK6FYN | |
| SCHEMBL4824130 | 0.82 | LCK (0.59) | SRCLCKTEKABL1FYN | |
| SCHEMBL4824137 | 0.82 | LCK (0.59) | SRCLCKTEKABL1FYN | |
| Acetic Acid SCHEMBL6433582 | 0.81 | LCK (0.58) | SRCLCKTEKABL1FYN | |
| Acetic Acid SCHEMBL4822823 | 0.80 | LCK (0.57) | SRCLCKTEKABL1FYN | |
| SCHEMBL4821450 | 0.80 | LCK (0.57) | SRCLCKTEKABL1FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660744-B1 | Kinase inhibitors | ABBOTT GMBH & CO. KG (DE) | 2003-12-09 | — | — | US | disclosed |